BAK1 Produkte
(BCL2-Antagonist/killer 1 (BAK1))
Kategorien
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008].
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Ausgewählte BAK1 Kategorien
BAK1 Antikörper
High quality antibodies with extensive validation data.
BAK1 ELISA Kits
Reliable ELISA kits for a wide range of species.
BAK1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene BAK1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ELISA, FACS, ICC, Neut
Validierungen
- (6)
Kat. Nr.
ABIN5611250
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IP
Validierungen
- (8)
Kat. Nr.
ABIN3020677
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC (p)
Validierungen
- (2)
- (10)
Kat. Nr.
ABIN3042342
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene BAK1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965129
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965130
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6954055
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene BAK1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1346390
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1346392
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7396205
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren BAK1 Produkten
: "YWHAZ amplification/overexpression defines aggressive bladder cancer and contributes to chemo-/radio-resistance by suppressing caspase-mediated apoptosis." in: The Journal of pathology, (2019) (PubMed).: "Copper induces oxidative stress and apoptosis through mitochondria-mediated pathway in chicken hepatocytes." in: Toxicology in vitro : an international journal published in association with BIBRA, Vol. 54, pp. 310-316, (2019) (PubMed).
: "MicroRNA-29c Correlates with Neuroprotection Induced by FNS by Targeting Both Birc2 and Bak1 in Rat Brain after Stroke." in: CNS neuroscience & therapeutics, Vol. 21, Issue 6, pp. 496-503, (2016) (PubMed).
: "Paraquat Induces Cell Death Through Impairing Mitochondrial Membrane Permeability." in: Molecular neurobiology, (2015) (PubMed).
: "Ovatodiolide sensitizes aggressive breast cancer cells to doxorubicin, eliminates their cancer stem cell-like phenotype, and reduces doxorubicin-associated toxicity." in: Cancer letters, Vol. 364, Issue 2, pp. 125-34, (2015) (PubMed).
: "Notch4 Signaling Confers Susceptibility to TRAIL-Induced Apoptosis in Breast Cancer Cells." in: Journal of cellular biochemistry, Vol. 116, Issue 7, pp. 1371-80, (2015) (PubMed).
: "Regulation of cell transformation by Rb-controlled redox homeostasis." in: PLoS ONE, Vol. 9, Issue 7, pp. e102582, (2014) (PubMed).
: "The C-terminal domain (CTD) in linker histones antagonizes anti-apoptotic proteins to modulate apoptotic outcomes at the mitochondrion." in: Cell death & disease, Vol. 5, pp. e1058, (2014) (PubMed).
: "Systems analysis of BCL2 protein family interactions establishes a model to predict responses to chemotherapy." in: Cancer research, Vol. 73, Issue 2, pp. 519-28, (2013) (PubMed).
: "Disruption of the VDAC2-Bak interaction by Bcl-x(S) mediates efficient induction of apoptosis in melanoma cells." in: Cell death and differentiation, Vol. 19, Issue 12, pp. 1928-38, (2012) (PubMed).
Synonyme und alternative Namen zu BAK1
BCL2 antagonist/killer 1 (BAK1), BCL2-antagonist/killer 1 (Bak1), BCL2 antagonist/killer 1 (Bak1), BCL2 antagonist/killer 1 L homeolog (bak1.L), BAK, Bak, bak, BAK-LIKE, Bak1, bak1, BCL2L7, CDN1, N-Bak, N-BAK1Bezeichner auf Proteinebene für BAK1
- BCL2-like 7 protein
- apoptosis regulator BAK
- bcl-2 homologous antagonist/killer
- bcl-2-like protein 7
- bcl2-L-7
- pro-apoptotic protein BAK
- Bcl2 homologous antagonist/killer
- Bcl-2-like 7
- BCL2 antagonist/killer 1 L homeolog
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