BCAR3 Produkte
(Breast Cancer Anti-Estrogen Resistance 3 (BCAR3))
Kategorien
Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012].
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Ausgewählte BCAR3 Kategorien
BCAR3 Antikörper
High quality antibodies with extensive validation data.
BCAR3 ELISA Kits
Reliable ELISA kits for a wide range of species.
BCAR3 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene BCAR3 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Rat
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (4)
Kat. Nr.
ABIN6260215
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (3)
Kat. Nr.
ABIN6257959
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (2)
Kat. Nr.
ABIN563616
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene BCAR3 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965237
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6954192
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN5648159
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene BCAR3 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1346502
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7414060
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN2715176
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren BCAR3 Produkten
: "Protein tyrosine phosphatase α phosphotyrosyl-789 binds BCAR3 to position Cas for activation at integrin-mediated focal adhesions." in: Molecular and cellular biology, Vol. 32, Issue 18, pp. 3776-89, (2012) (PubMed).: "Breast cancer antiestrogen resistance-3 expression regulates breast cancer cell migration through promotion of p130Cas membrane localization and membrane ruffling." in: Cancer research, Vol. 67, Issue 13, pp. 6174-82, (2007) (PubMed).
: "Identification of BCAR3 by a random search for genes involved in antiestrogen resistance of human breast cancer cells." in: The EMBO journal, Vol. 17, Issue 10, pp. 2799-808, (1998) (PubMed).
Synonyme und alternative Namen zu BCAR3
breast cancer anti-estrogen resistance 3 (BCAR3), breast cancer anti-estrogen resistance 3 (Bcar3), breast cancer anti-estrogen resistance 3 (bcar3), breast cancer anti-estrogen resistance 3 L homeolog (bcar3.L), AI131758, AND-34, BCAR3, NSP2, SH2D3BBezeichner auf Proteinebene für BCAR3
- SH2 domain-containing protein 3B
- breast cancer anti-estrogen resistance protein 3
- breast cancer antiestrogen resistance 3 protein
- dJ1033H22.2 (breast cancer anti-estrogen resistance 3)
- novel SH2-containing protein 2
- p130Cas-binding protein AND-34
- breast cancer anti-estrogen resistance 3
- breast cancer antiestrogen resistance 3
- breast cancer anti-estrogen resistance protein 3-like
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