BCL11A Produkte
(B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))
Kategorien
This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte BCL11A Kategorien
BCL11A Antikörper
High quality antibodies with extensive validation data.
BCL11A ELISA Kits
Reliable ELISA kits for a wide range of species.
BCL11A Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene BCL11A Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p), IF
Validierungen
- (5)
Kat. Nr.
ABIN526947
Menge
100 μg
Datenblatt
Datenblatt
Applikation
WB, IHC, IHC (p)
Validierungen
- (4)
Kat. Nr.
ABIN6741578
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7145171
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene BCL11A ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6954027
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6223083
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1123168
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene BCL11A Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1346538
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1346540
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7407040
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren BCL11A Produkten
: "A natural regulatory mutation in the proximal promoter elevates fetal globin expression by creating a de novo GATA1 site." in: Blood, Vol. 133, Issue 8, pp. 852-856, (2019) (PubMed).: "Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding." in: Nature genetics, Vol. 50, Issue 4, pp. 498-503, (2018) (PubMed).
: "Bcl11a controls Flt3 expression in early hematopoietic progenitors and is required for pDC development in vivo." in: PLoS ONE, Vol. 8, Issue 5, pp. e64800, (2013) (PubMed).
: "Transcriptional silencing of {gamma}-globin by BCL11A involves long-range interactions and cooperation with SOX6." in: Genes & development, Vol. 24, Issue 8, pp. 783-98, (2010) (PubMed).
: "BCL11A represses HBG transcription in K562 cells." in: Blood cells, molecules & diseases, Vol. 42, Issue 2, pp. 144-9, (2009) (PubMed).
: "Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 5, pp. 1620-5, (2008) (PubMed).
: "Novel markers of normal and neoplastic human plasmacytoid dendritic cells." in: Blood, Vol. 111, Issue 7, pp. 3778-92, (2008) (PubMed).
: "Functional studies of BCL11A: characterization of the conserved BCL11A-XL splice variant and its interaction with BCL6 in nuclear paraspeckles of germinal center B cells." in: Molecular cancer, Vol. 5, pp. 18, (2006) (PubMed).
: "The BCL11AXL transcription factor: its distribution in normal and malignant tissues and use as a marker for plasmacytoid dendritic cells." in: Leukemia, Vol. 20, Issue 8, pp. 1439-41, (2006) (PubMed).
: "Hydroxyurea differentially modulates activator and repressors of γ-globin gene in erythroblasts of responsive and non-responsive patients with sickle cell disease in correlation with Index of ..." in: Haematologica, Vol. 102, Issue 12, pp. 1995-2004 (PubMed).
Synonyme und alternative Namen zu BCL11A
B cell CLL/lymphoma 11A (zinc finger protein) (Bcl11a), B-cell CLL/lymphoma 11A (BCL11A), B-cell CLL/lymphoma 11A L homeolog (bcl11a.L), B-cell CLL/lymphoma 11A (Bcl11a), B-cell CLL/lymphoma 11Aa (bcl11aa), 2810047E18Rik, BCL-11A, bcl11a, BCL11A-L, BCL11a-M, BCL11A-S, BCL11A-XL, Ctip1, CTIP1, D930021L15Rik, Evi9, EVI9, Evi9a, Evi9b, Evi9c, HBFQTL5, mKIAA1809, wu:fi09f10, zgc:136898, ZNF856Bezeichner auf Proteinebene für BCL11A
- B-cell CLL/lymphoma 11A (zinc finger protein)
- B-cell lymphoma/leukemia 11A
- COUP-TF interacting protein 1
- COUP-TF-interacting protein 1
- EVI-9
- ecotropic viral integration site 9 protein
- myeloid leukemia
- B-cell CLL/lymphoma 11A (zinc finger protein) isoform 2
- BCL-11A
- BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) isoform 1
- C2H2-type zinc finger protein
- ecotropic viral integration site 9 homolog
- ecotropic viral integration site 9 protein homolog
- zinc finger protein 856
- B-cell CLL/lymphoma 11A
- bcl11a.1
- fi09f10
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