BIK Produkte
(BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))
Kategorien
The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins. [provided by RefSeq, Sep 2011].
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Ausgewählte BIK Kategorien
BIK Antikörper
High quality antibodies with extensive validation data.
BIK ELISA Kits
Reliable ELISA kits for a wide range of species.
BIK Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene BIK Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC, ELISA, IF, ICC
Validierungen
- (5)
Kat. Nr.
ABIN6260261
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC (p), FACS
Validierungen
- (6)
Kat. Nr.
ABIN4950330
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN388114
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene BIK ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1380102
Menge
2 x 96 tests
Datenblatt
Datenblatt
Empfohlene BIK Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1346675
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1346677
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3131975
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren BIK Produkten
: "β-arrestin-2 enhances intestinal epithelial apoptosis in necrotizing enterocolitis." in: Aging, Vol. 11, Issue 19, pp. 8294-8312, (2019) (PubMed).: "Methotrexate upregulates circadian transcriptional factors PAR bZIP to induce apoptosis on rheumatoid arthritis synovial fibroblasts." in: Arthritis research & therapy, Vol. 20, Issue 1, pp. 55, (2018) (PubMed).
: "Targeting SQSTM1/p62 induces cargo loading failure and converts autophagy to apoptosis via NBK/Bik." in: Molecular and cellular biology, Vol. 34, Issue 18, pp. 3435-49, (2014) (PubMed).
: "Deficiency of Bim in dendritic cells contributes to overactivation of lymphocytes and autoimmunity." in: Blood, Vol. 109, Issue 10, pp. 4360-7, (2007) (PubMed).
: "TNF pretreatment interferes with mitochondrial apoptosis in the mouse liver by A20-mediated down-regulation of Bax." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 10, pp. 7042-9, (2007) (PubMed).
: "The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through ..." in: The Journal of biological chemistry, Vol. 281, Issue 35, pp. 25850-66, (2006) (PubMed).
: "Transcriptional activation of the proapoptotic bik gene by E2F proteins in cancer cells." in: FEBS letters, Vol. 580, Issue 25, pp. 5905-9, (2006) (PubMed).
: "Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis." in: The EMBO journal, Vol. 24, Issue 8, pp. 1546-56, (2005) (PubMed).
: "BH3-only BIK regulates BAX,BAK-dependent release of Ca2+ from endoplasmic reticulum stores and mitochondrial apoptosis during stress-induced cell death." in: The Journal of biological chemistry, Vol. 280, Issue 25, pp. 23829-36, (2005) (PubMed).
: "BH-3-only BIK functions at the endoplasmic reticulum to stimulate cytochrome c release from mitochondria." in: The Journal of biological chemistry, Vol. 277, Issue 20, pp. 18053-60, (2002) (PubMed).
Synonyme und alternative Namen zu BIK
BCL2 interacting killer (BIK), BCL2-interacting killer (Bik), BCL2-interacting killer (apoptosis-inducing) (bik), BIK, Biklk, BIP1, Blk, BP4, Nbk, NBK, si:dkey-31f5.6Bezeichner auf Proteinebene für BIK
- BCL2-interacting killer (apoptosis-inducing)
- BCL2-interacting killer
- apoptosis inducer NBK
- bcl-2-interacting killer
- bik-like killer protein
- apoptosis-inducing NBK
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