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BLM Produkte

(Bloom Syndrome RecQ Like Helicase (BLM))
The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination. [provided by RefSeq, Jul 2008].

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Ausgewählte BLM Kategorien

BLM Antikörper

High quality antibodies with extensive validation data.

BLM ELISA Kits

Reliable ELISA kits for a wide range of species.

BLM Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene BLM Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Applikation WB, IF, IHC (p), ICC
Validierungen
  • (4)
Kat. Nr. ABIN2855003
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC
Validierungen
  • (2)
Kat. Nr. ABIN7138888
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, FACS
Validierungen
  • (2)
Kat. Nr. ABIN651053
Menge 400 μL
Datenblatt Datenblatt

Empfohlene BLM ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method
Validierungen
Kat. Nr. ABIN1123945
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1123947
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Chicken
Analytical Method
Validierungen
Kat. Nr. ABIN1123946
Menge 96 tests
Datenblatt Datenblatt

Empfohlene BLM Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1346713
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3089946
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3132191
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren BLM Produkten

Yoshimura: "Increased error-free DNA repair gene expression through reprogramming in human iPS cells." in: Regenerative therapy, Vol. 11, pp. 101-105, (2019) (PubMed).

Nicholls, Nadalutti, Motori, Sommerville, Gorman, Basu, Hoberg, Turnbull, Chinnery, Larsson, Larsson, Falkenberg, Taylor, Griffith, Gustafsson: "Topoisomerase 3α Is Required for Decatenation and Segregation of Human mtDNA." in: Molecular cell, Vol. 69, Issue 1, pp. 9-23.e6, (2018) (PubMed).

Arora, Abdel-Fatah, Agarwal, Doherty, Moseley, Aleskandarany, Green, Ball, Alshareeda, Rakha, Chan, Ellis, Madhusudan: "Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer." in: Molecular cancer therapeutics, Vol. 14, Issue 4, pp. 1057-65, (2015) (PubMed).

Meena, Cerutti, Beichler, Morita, Bruhn, Kumar, Kraus, Speicher, Wang, Kestler, dAdda di Fagagna, Günes, Rudolph: "Telomerase abrogates aneuploidy-induced telomere replication stress, senescence and cell depletion." in: The EMBO journal, Vol. 34, Issue 10, pp. 1371-84, (2015) (PubMed).

Murfuni, Nicolai, Baldari, Crescenzi, Bignami, Franchitto, Pichierri: "The WRN and MUS81 proteins limit cell death and genome instability following oncogene activation." in: Oncogene, Vol. 32, Issue 5, pp. 610-20, (2013) (PubMed).

Lao, Welcsh, Luo, Carter, Dzieciatkowski, Dintzis, Meza, Sarvetnick, Monnat, Loeb, Grady: "Altered RECQ Helicase Expression in Sporadic Primary Colorectal Cancers." in: Translational oncology, Vol. 6, Issue 4, pp. 458-69, (2013) (PubMed).

Srivastava, Modi, Tripathi, Mudgal, De, Sengupta: "BLM helicase stimulates the ATPase and chromatin-remodeling activities of RAD54." in: Journal of cell science, Vol. 122, Issue Pt 17, pp. 3093-103, (2009) (PubMed).

Nair, Emmons, Cress, Argilagos, Lam, Kerr, Wang, Dalton, Hazlehurst: "HYD1-induced increase in reactive oxygen species leads to autophagy and necrotic cell death in multiple myeloma cells." in: Molecular cancer therapeutics, Vol. 8, Issue 8, pp. 2441-51, (2009) (PubMed).

Shimura, Torres, Martin, Rao, Pommier, Katsura, Miyagawa, Aladjem: "Bloom's syndrome helicase and Mus81 are required to induce transient double-strand DNA breaks in response to DNA replication stress." in: Journal of molecular biology, Vol. 375, Issue 4, pp. 1152-64, (2008) (PubMed).

Tripathi, Nagarjuna, Sengupta: "BLM helicase-dependent and -independent roles of 53BP1 during replication stress-mediated homologous recombination." in: The Journal of cell biology, Vol. 178, Issue 1, pp. 9-14, (2007) (PubMed).

Synonyme und alternative Namen zu BLM

Bloom syndrome RecQ like helicase (BLM), Bloom syndrome RecQ like helicase S homeolog (blm.S), Bloom syndrome RecQ like helicase (Blm), Bloom syndrome, RecQ like helicase (Blm), blm-A, BS, ORF1, RECQ2, RECQL2, RECQL3, xBLM

Bezeichner auf Proteinebene für BLM

  • Bloom syndrome protein
  • DNA helicase, RecQ-like type 2
  • recQ protein-like 3
  • Bloom syndrome, RecQ helicase-like
  • Bloom syndrome protein homolog
  • recQ helicase homolog
  • BLM helicase
  • Gd BLM
  • Bloom syndrome homolog
  • mBLM
  • Bloom syndrome protein-like
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