BMPR2 Produkte
(Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))
Kategorien
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, Jul 2008].
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Ausgewählte BMPR2 Kategorien
BMPR2 Antikörper
High quality antibodies with extensive validation data.
BMPR2 ELISA Kits
Reliable ELISA kits for a wide range of species.
BMPR2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene BMPR2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, ICC
Validierungen
- (2)
- (4)
Kat. Nr.
ABIN968988
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (2)
- (4)
Kat. Nr.
ABIN968987
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, IHC, FACS
Validierungen
- (7)
Kat. Nr.
ABIN3030192
Menge
0.4 mL
Datenblatt
Datenblatt
Empfohlene BMPR2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965212
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6962060
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6954156
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene BMPR2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1346791
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7505025
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Human Cells
Validierungen
Kat. Nr.
ABIN7318203
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren BMPR2 Produkten
: "TGF‑β1 affects the renal cancer miRNome and regulates tumor cells proliferation." in: International journal of molecular medicine, Vol. 49, Issue 4, (2022) (PubMed).: "MicroRNA-155 inhibits the osteogenic differentiation of mesenchymal stem cells induced by BMP9 via downregulation of BMP signaling pathway." in: International journal of molecular medicine, Vol. 41, Issue 6, pp. 3379-3393, (2018) (PubMed).
: "Baicalein attenuates monocrotaline-induced pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition." in: Life sciences, Vol. 207, pp. 442-450, (2018) (PubMed).
: "BMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-β receptor type I ALK5." in: PLoS ONE, Vol. 12, Issue 5, pp. e0177188, (2017) (PubMed).
: "Endocytosis contributes to BMP2-induced Smad signalling and neuronal growth." in: Neuroscience letters, Vol. 643, pp. 32-37, (2017) (PubMed).
: "Correlating the Effects of Bone Morphogenic Protein to Secreted Soluble Factors from Fibroblasts and Mesenchymal Stem Cells in Regulating Regenerative Processes In Vitro." in: Tissue engineering. Part A, (2014) (PubMed).
: "BMP signaling induces astrocytic differentiation of clinically derived oligodendroglioma propagating cells." in: Molecular cancer research : MCR, Vol. 12, Issue 2, pp. 283-94, (2014) (PubMed).
: "Epigenetic repression of bone morphogenetic protein receptor II expression in scleroderma." in: Journal of cellular and molecular medicine, Vol. 17, Issue 10, pp. 1291-9, (2014) (PubMed).
: "Roles of miR-1-1 and miR-181c in ventricular septal defects." in: International journal of cardiology, Vol. 168, Issue 2, pp. 1441-6, (2013) (PubMed).
: "Bone morphogenetic protein-9 activates Smad and ERK pathways and supports human osteoclast function and survival in vitro." in: Cellular signalling, Vol. 25, Issue 4, pp. 717-28, (2013) (PubMed).
Synonyme und alternative Namen zu BMPR2
bone morphogenetic protein receptor type 2 (BMPR2), bone morphogenetic protein receptor, type II b (serine/threonine kinase) (bmpr2b), bone morphogenetic protein receptor, type II (serine/threonine kinase) (Bmpr2), bone morphogenetic protein receptor type 2 (Bmpr2), 2610024H22Rik, AL117858, AW546137, BB189135, BMP-2, BMPR-2, BMPR-II, Bmpr-II, BMPR3, BMPRII, bmprii, BMR2, BRK-3, Gm20272, PPH1, T-ALKBezeichner auf Proteinebene für BMPR2
- bone morphogenetic protein receptor type II
- bone morphogenetic protein receptor type-2
- bone morphogenetic protein receptor type II b
- BMP type II receptor
- BMP type-2 receptor
- BMPR-2
- type II activin receptor-like kinase
- type II receptor for bone morphogenetic protein-4
- bone morphogenic protein receptor, type II (serine/threonine kinase)
- bone morphogenic protein receptor type 2
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