BMX Produkte
(BMX Non-Receptor Tyrosine Kinase (BMX))
Kategorien
This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
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Ausgewählte BMX Kategorien
BMX Antikörper
High quality antibodies with extensive validation data.
BMX ELISA Kits
Reliable ELISA kits for a wide range of species.
BMX Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene BMX Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p), ICC, IHC (fro)
Validierungen
- (4)
Kat. Nr.
ABIN7443482
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC, ELISA, IF, ICC
Validierungen
- (4)
Kat. Nr.
ABIN6261616
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ELISA, IF
Validierungen
- (3)
Kat. Nr.
ABIN7184420
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene BMX ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965180
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6954117
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN5691925
Menge
2 x 96 tests
Datenblatt
Datenblatt
Empfohlene BMX Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1346793
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN2715316
Menge
20 μg
Datenblatt
Datenblatt
Reaktivität
Rat
Source
Insect Cells
Validierungen
Kat. Nr.
ABIN5509204
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren BMX Produkten
: "BMX Negatively Regulates BAK Function, Thereby Increasing Apoptotic Resistance to Chemotherapeutic Drugs." in: Cancer research, Vol. 75, Issue 7, pp. 1345-55, (2015) (PubMed).: "Estradiol modulates tumor necrosis factor-induced endothelial inflammation: role of tumor necrosis factor receptor 2." in: Journal of vascular research, Vol. 50, Issue 1, pp. 21-34, (2012) (PubMed).
: "The tyrosine kinase BMX is an essential mediator of inflammatory arthritis in a kinase-independent manner." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 10, pp. 6014-23, (2011) (PubMed).
: "Bmx tyrosine kinase regulates TLR4-induced IL-6 production in human macrophages independently of p38 MAPK and NFkapp}B activity." in: Blood, Vol. 111, Issue 4, pp. 1781-8, (2008) (PubMed).
: "Bone marrow X kinase-mediated signal transduction in irradiated vascular endothelium." in: Cancer research, Vol. 68, Issue 8, pp. 2861-9, (2008) (PubMed).
: "A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling." in: Nature cell biology, Vol. 7, Issue 8, pp. 797-807, (2005) (PubMed).
: "Identification of phosphorylation sites within the SH3 domains of Tec family tyrosine kinases." in: Biochimica et biophysica acta, Vol. 1645, Issue 2, pp. 123-32, (2003) (PubMed).
: "Functional interaction of caveolin-1 with Bruton's tyrosine kinase and Bmx." in: The Journal of biological chemistry, Vol. 277, Issue 11, pp. 9351-7, (2002) (PubMed).
: "Interaction between tyrosine kinase Etk and a RUN domain- and FYVE domain-containing protein RUFY1. A possible role of ETK in regulation of vesicle trafficking." in: The Journal of biological chemistry, Vol. 277, Issue 33, pp. 30219-26, (2002) (PubMed).
: "Etk/Bmx as a tumor necrosis factor receptor type 2-specific kinase: role in endothelial cell migration and angiogenesis." in: Molecular and cellular biology, Vol. 22, Issue 21, pp. 7512-23, (2002) (PubMed).
Synonyme und alternative Namen zu BMX
BMX non-receptor tyrosine kinase (BMX), BMX non-receptor tyrosine kinase (bmx), BMX non-receptor tyrosine kinase (Bmx), BMX, ETK, Etk, Etk/Bmx, PSCTK2, PSCTK3, RGD1565643, Tyro8Bezeichner auf Proteinebene für BMX
- BMX non-receptor tyrosine kinase
- cytoplasmic tyrosine-protein kinase BMX-like
- BTK-like on X chromosome
- Etk/Bmx cytosolic tyrosine kinase
- NTK38 tyrosine kinase
- bone marrow tyrosine kinase gene in chromosome X protein
- cytoplasmic tyrosine-protein kinase BMX
- epithelial and endothelial tyrosine kinase
- TYRO8 protein tyrosine kinase 8
- bone marrow tyrosine kinase gene in chromosome X protein homolog
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