BRCA2 Produkte
(Breast Cancer 2, Early Onset (BRCA2))
Kategorien
Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele. [provided by RefSeq, Dec 2008].
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Ausgewählte BRCA2 Kategorien
BRCA2 Antikörper
High quality antibodies with extensive validation data.
BRCA2 ELISA Kits
Reliable ELISA kits for a wide range of species.
BRCA2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene BRCA2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p)
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN673434
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Rat
Applikation
WB, IHC, IF
Validierungen
- (7)
Kat. Nr.
ABIN7234156
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (3)
Kat. Nr.
ABIN7433543
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene BRCA2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6954189
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6954190
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Pig
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN778240
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene BRCA2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7122032
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1346849
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7504959
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren BRCA2 Produkten
: "Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks." in: Nature communications, Vol. 9, Issue 1, pp. 3882, (2019) (PubMed).: "Expression characteristics of FHIT, p53, BRCA2 and MLH1 in families with a history of oesophageal cancer in a region with a high incidence of oesophageal cancer." in: Oncology letters, Vol. 9, Issue 1, pp. 430-436, (2015) (PubMed).
: "DNA repair biomarker profiling of head and neck cancer: Ku80 expression predicts locoregional failure and death following radiotherapy." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 7, pp. 2035-43, (2011) (PubMed).
: "Differential expressions of BRCA1 and BRCA2 in infantile gynecomastia." in: Anticancer research, Vol. 24, Issue 1, pp. 321-4, (2004) (PubMed).
: "BRCA1 and BRCA2 protein expressions in an ovotestis of a 46, XX true hermaphrodite." in: Breast cancer research : BCR, Vol. 3, Issue 1, pp. 61-5, (2001) (PubMed).
: "Induction of the BRCA2 promoter by nuclear factor-kappa B." in: The Journal of biological chemistry, Vol. 275, Issue 45, pp. 35548-56, (2000) (PubMed).
: "Low-Dose Ionizing Radiation Affects Mesenchymal Stem Cells via Extracellular Oxidized Cell-Free DNA: A Possible Mediator of Bystander Effect and Adaptive Response." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 9515809 (PubMed).
Synonyme und alternative Namen zu BRCA2
BRCA2, DNA repair associated (BRCA2), Breast cancer 2, early onset homolog (Brca2), BRCA2, DNA repair associated (Brca2), breast cancer 2, early onset (brca2), breast cancer 2, early onset (LOC584780), BRCA2, DNA repair associated (brca2), breast cancer 2, early onset (Brca2), 30169, AI256696, AW045498, BcDNA:SD25109, brca2, BRCA2, BRCC2, brcc2, BROVCA2, brovca2, CG13583, CG13584, CG30169, dmbrca2, Dmel\\CG30169, FACD, facd, FAD, fad, FAD1, fad1, FANCB, fancb, FANCD, FANCD1, fancd1, Fancd1, GLM3, PNCA2, RAB163Bezeichner auf Proteinebene für BRCA2
- BRCA1/BRCA2-containing complex, subunit 2
- breast and ovarian cancer susceptibility gene, early onset
- breast cancer 2 tumor suppressor
- breast cancer type 2 susceptibility protein
- fanconi anemia group D1 protein
- truncated breast and ovarian cancer susceptibility protein 2
- breast cancer 2, early onset homolog
- CG30169-PA
- Brca2-PA
- breast cancer 2, mutation 1, University of Wisconsin-Madison
- breast cancer susceptibility protein 2
- breast cancer type 2 susceptibility protein homolog
- fanconi anemia group D1 protein homolog
- breast and ovarian cancer susceptibility protein 2
- breast cancer 2, early onset
- breast cancer type 2 susceptibility protein-like
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