BRCC3 Produkte
(BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3))
Kategorien
This gene encodes a subunit of the BRCA1-BRCA2-containing complex (BRCC), which is an E3 ubiquitin ligase. This complex plays a role in the DNA damage response, where it is responsible for the stable accumulation of BRCA1 at DNA break sites. The component encoded by this gene can specifically cleave Lys 63-linked polyubiquitin chains, and it regulates the abundance of these polyubiquitin chains in chromatin. The loss of this gene results in abnormal angiogenesis and is associated with syndromic moyamoya, a cerebrovascular angiopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Jun 2011].
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Ausgewählte BRCC3 Kategorien
BRCC3 Antikörper
High quality antibodies with extensive validation data.
BRCC3 ELISA Kits
Reliable ELISA kits for a wide range of species.
BRCC3 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene BRCC3 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (4)
Kat. Nr.
ABIN7158679
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (3)
Kat. Nr.
ABIN7158678
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN462274
Menge
50 μL
Datenblatt
Datenblatt
Empfohlene BRCC3 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6954187
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN2945768
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene BRCC3 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1346851
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7414093
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Insect Cells
Validierungen
Kat. Nr.
ABIN3134114
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren BRCC3 Produkten
: "SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy." in: PLoS pathogens, Vol. 14, Issue 5, pp. e1007071, (2018) (PubMed).: "miR-3940-5p associated with genetic damage in workers exposed to hexavalent chromium." in: Toxicology letters, Vol. 229, Issue 1, pp. 319-26, (2014) (PubMed).
: "BRCC36 is essential for ionizing radiation-induced BRCA1 phosphorylation and nuclear foci formation." in: Cancer research, Vol. 66, Issue 10, pp. 5039-46, (2006) (PubMed).
: "Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair." in: Molecular cell, Vol. 12, Issue 5, pp. 1087-99, (2003) (PubMed).
Synonyme und alternative Namen zu BRCC3
BRCA1/BRCA2-containing complex subunit 3 (BRCC3), DEP domain containing 1B (depdc1b), BRCA1/BRCA2-containing complex subunit 3 (brcc3), BRCA1/BRCA2-containing complex, subunit 3 (Brcc3), BRCA1/BRCA2-containing complex subunit 3 L homeolog (brcc3.L), BRCC3, brcc3, BRCC36, brcc36, C6.1A, CXorf53, xtp1Bezeichner auf Proteinebene für BRCC3
- BRCA1/BRCA2-containing complex, subunit 3
- c6.1A
- BRCA1-A complex subunit BRCC36
- BRCA1/BRCA2-containing complex subunit 3
- BRCA1/BRCA2-containing complex subunit 36
- BRISC complex subunit BRCC36
- lys-63-specific deubiquitinase BRCC36
- 6.1A protein
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