BRD4 Produkte
(Bromodomain Containing 4 (BRD4))
Kategorien
The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15\;19)(q13\;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008].
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Ausgewählte BRD4 Kategorien
BRD4 Antikörper
High quality antibodies with extensive validation data.
BRD4 ELISA Kits
Reliable ELISA kits for a wide range of species.
BRD4 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene BRD4 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
IHC, IF
Validierungen
- (4)
Kat. Nr.
ABIN7010051
Menge
60 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC
Validierungen
- (4)
Kat. Nr.
ABIN6137653
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (4)
Kat. Nr.
ABIN6260309
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene BRD4 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965241
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6954198
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1124204
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene BRD4 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7122050
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7319875
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN6964231
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren BRD4 Produkten
: "BRD4 regulates fructose-inducible lipid accumulation-related genes in the mouse liver." in: Metabolism: clinical and experimental, Vol. 65, Issue 10, pp. 1478-88, (2017) (PubMed).: "H2A.Z.1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs." in: Cell reports, Vol. 14, Issue 5, pp. 1142-55, (2016) (PubMed).
: "Chromatin remodelling and autocrine TNFα are required for optimal interleukin-6 expression in activated human neutrophils." in: Nature communications, Vol. 6, pp. 6061, (2015) (PubMed).
: "The oncogenic BRD4-NUT chromatin regulator drives aberrant transcription within large topological domains." in: Genes & development, Vol. 29, Issue 14, pp. 1507-23, (2015) (PubMed).
: "The elongation complex components BRD4 and MLLT3/AF9 are transcriptional coactivators of nuclear retinoid receptors." in: PLoS ONE, Vol. 8, Issue 6, pp. e64880, (2013) (PubMed).
: "The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3." in: Molecular and cellular biology, Vol. 31, Issue 13, pp. 2641-52, (2011) (PubMed).
: "RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia." in: Nature, Vol. 478, Issue 7370, pp. 524-8, (2011) (PubMed).
: "Targeting MYC dependence in cancer by inhibiting BET bromodomains." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 40, pp. 16669-74, (2011) (PubMed).
: "NCoR1 mediates papillomavirus E8;E2C transcriptional repression." in: Journal of virology, Vol. 84, Issue 9, pp. 4451-60, (2010) (PubMed).
: "Proteasomal degradation of the papillomavirus E2 protein is inhibited by overexpression of bromodomain-containing protein 4." in: Journal of virology, Vol. 83, Issue 9, pp. 4127-39, (2009) (PubMed).
Synonyme und alternative Namen zu BRD4
bromodomain containing 4 L homeolog (brd4.L), bromodomain containing 4 (BRD4), bromodomain containing 4 (brd4), bromodomain-containing protein 4 (LOC100409351), bromodomain containing 4 (Brd4), BRD4, brd4-b, Brd5, CAP, fb18g03, HUNK1, HUNKI, MCAP, WI-11513, wu:fb18g03Bezeichner auf Proteinebene für BRD4
- Bromodomain-containing protein 4B
- bromodomain-containing protein 4B
- bromodomain containing 4
- bromodomain-containing protein 4
- bromodomain 4
- bromodomain-containing protein 4-like
- bromodomain containing protein 4
- bromodomain-containing 4
- chromosome-associated protein
- bromodomain-containing 5
- fsh-like protein
- mitotic chromosome-associated protein
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