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BTK Produkte

(Bruton Agammaglobulinemia tyrosine Kinase (BTK))
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. [provided by RefSeq, Nov 2008].

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Ausgewählte BTK Kategorien

BTK Antikörper

High quality antibodies with extensive validation data.

BTK ELISA Kits

Reliable ELISA kits for a wide range of species.

BTK Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene BTK Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC
Validierungen
  • (5)
Kat. Nr. ABIN3022171
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (4)
Kat. Nr. ABIN7265950
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC
Validierungen
  • (5)
Kat. Nr. ABIN3030207
Menge 0.4 mL
Datenblatt Datenblatt

Empfohlene BTK ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validierungen
  • (3)
Kat. Nr. ABIN1981713
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6965243
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6965242
Menge 96 tests
Datenblatt Datenblatt

Empfohlene BTK Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1346956
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1346958
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN7491289
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren BTK Produkten

Yu, Bondada, Ghoshal, Singh, Pistilli, Dayaram, Iqbal, Sands, Davis, Bondada, Geddes: "Repositioning Flubendazole for Spinal Cord Injury." in: Journal of neurotrauma, (2019) (PubMed).

Liu, Zhang, Han, Wang, Liu, Zhang, Zhou, Xiang: "Inhibition of BTK protects lungs from trauma-hemorrhagic shock-induced injury in rats." in: Molecular medicine reports, Vol. 16, Issue 1, pp. 192-200, (2017) (PubMed).

Hoshino, Okuno, Migita, Ban, Yang, Kiyokawa, Adachi, Kojima, Ohara, Kanegane: "X-linked agammaglobulinemia associated with B-precursor acute lymphoblastic leukemia." in: Journal of clinical immunology, Vol. 35, Issue 2, pp. 108-11, (2015) (PubMed).

Wang, Iwata, Nakayamada, Niiro, Jabbarzadeh-Tabrizi, Kondo, Kubo, Yoshikawa, Tanaka: "Amplification of IL-21 signalling pathway through Bruton's tyrosine kinase in human B cell activation." in: Rheumatology (Oxford, England), Vol. 54, Issue 8, pp. 1488-97, (2015) (PubMed).

Guo, Liu, Bhardwaj, Yang, Changou, Ma, Mazloom, Chintapalli, Xiao, Xiao, Kumaresan, Sanchez, Yeh, Evans, Patterson, Lam, Kung: "Targeting Btk/Etk of prostate cancer cells by a novel dual inhibitor." in: Cell death & disease, Vol. 5, pp. e1409, (2014) (PubMed).

Eda, Santo, Cirstea, Yee, Scullen, Nemani, Mishima, Waterman, Arastu-Kapur, Evans, Singh, Kirk, Westlin, Raje et al.: "A novel Bruton's tyrosine kinase inhibitor CC-292 in combination with the proteasome inhibitor carfilzomib impacts the bone microenvironment in a multiple myeloma model with resultant antimyeloma ..." in: Leukemia, Vol. 28, Issue 9, pp. 1892-901, (2014) (PubMed).

Gleixner, Peter, Blatt, Suppan, Reiter, Radia, Hadzijusufovic, Valent: "Synergistic growth-inhibitory effects of ponatinib and midostaurin (PKC412) on neoplastic mast cells carrying KIT D816V." in: Haematologica, Vol. 98, Issue 9, pp. 1450-7, (2013) (PubMed).

Krupa, Fudala, Florence, Tucker, Allen, Standiford, Luchowski, Fol, Rahman, Gryczynski, Gryczynski, Kurdowska: "Bruton's tyrosine kinase mediates FcγRIIa/Toll-like receptor-4 receptor crosstalk in human neutrophils." in: American journal of respiratory cell and molecular biology, Vol. 48, Issue 2, pp. 240-9, (2013) (PubMed).

Lindvall, Blomberg, Väliaho, Vargas, Heinonen, Berglöf, Mohamed, Nore, Vihinen, Smith: "Bruton's tyrosine kinase: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling." in: Immunological reviews, Vol. 203, pp. 200-15, (2005) (PubMed).

Schimmer: "Inhibitor of apoptosis proteins: translating basic knowledge into clinical practice." in: Cancer research, Vol. 64, Issue 20, pp. 7183-90, (2004) (PubMed).

Synonyme und alternative Namen zu BTK

Bruton tyrosine kinase (BTK), Bruton agammaglobulinemia tyrosine kinase (btk), Bruton tyrosine kinase (btk), Bruton agammaglobulinemia tyrosine kinase (Btk), Bruton tyrosine kinase (Btk), agmx1, AGMX1, AI528679, AT, atk, ATK, bpk, BPK, BTK, imd1, IMD1, psctk1, PSCTK1, xid, xla, XLA

Bezeichner auf Proteinebene für BTK

  • Bruton agammaglobulinemia tyrosine kinase
  • B-cell progenitor kinase
  • agammaglobulinaemia tyrosine kinase
  • dominant-negative kinase-deficient Brutons tyrosine kinase
  • tyrosine-protein kinase BTK
  • tyrosine-protein kinase BTK isoform (lacking exon 14)
  • ATK
  • BPK
  • Bruton's tyrosine kinase
  • Tyrosine-protein kinase BTK (Brutons tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB)
  • X-linked immune deficiency
  • agammaglobulinemia tyrosine kinase
  • bruton tyrosine kinase
  • kinase EMB
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