BTRC Produkte
(beta-Transducin Repeat Containing (BTRC))
Kategorien
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class\; in addition to an F-box, this protein contains multiple WD-40 repeats. The encoded protein mediates degradation of CD4 via its interaction with HIV-1 Vpu. It has also been shown to ubiquitinate phosphorylated NFKBIA (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha), targeting it for degradation and thus activating nuclear factor kappa-B. Alternatively spliced transcript variants have been described. A related pseudogene exists in chromosome 6. [provided by RefSeq, Mar 2012].
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Ausgewählte BTRC Kategorien
BTRC Antikörper
High quality antibodies with extensive validation data.
BTRC ELISA Kits
Reliable ELISA kits for a wide range of species.
BTRC Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene BTRC Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, FACS
Validierungen
- (7)
Kat. Nr.
ABIN5611131
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (5)
Kat. Nr.
ABIN3022334
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IHC (p)
Validierungen
- (4)
Kat. Nr.
ABIN655814
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene BTRC ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN1743134
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Sheep
Analytical Method
Validierungen
Kat. Nr.
ABIN1774039
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Dog
Analytical Method
Validierungen
Kat. Nr.
ABIN1769143
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene BTRC Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1346979
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3092532
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3135065
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren BTRC Produkten
: "REST reduction is essential for hypoxia-induced neuroendocrine differentiation of prostate cancer cells by activating autophagy signaling." in: Oncotarget, Vol. 7, Issue 18, pp. 26137-51, (2018) (PubMed).: "Smad4 protein stability is regulated by ubiquitin ligase SCF beta-TrCP1." in: The Journal of biological chemistry, Vol. 279, Issue 15, pp. 14484-7, (2004) (PubMed).
: "Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition." in: Nature cell biology, Vol. 6, Issue 10, pp. 931-40, (2004) (PubMed).
: "Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage." in: Nature, Vol. 426, Issue 6962, pp. 87-91, (2003) (PubMed).
: "Identification of the receptor component of the IkappaBalpha-ubiquitin ligase." in: Nature, Vol. 396, Issue 6711, pp. 590-4, (1999) (PubMed).
: "A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif." in: Molecular cell, Vol. 1, Issue 4, pp. 565-74, (1998) (PubMed).
Synonyme und alternative Namen zu BTRC
beta-transducin repeat containing E3 ubiquitin protein ligase (BTRC), beta-transducin repeat containing E3 ubiquitin protein ligase (btrc), beta-transducin repeat containing (btrc), beta-TrCP (LOC100634006), beta-transducin repeat containing E3 ubiquitin protein ligase (Btrc), beta-transducin repeat containing E3 ubiquitin protein ligase S homeolog (btrc.S), beta-transducin repeat containing protein (Btrc), b-TrCP, Beta-TrCP, beta-TrCP, BETA-TRCP, beta-TrCP1, Beta-Trcp1, betaTrCP, BTRC, btrc, btrc-a, btrcp, bTrCP, btrcp1, bTrCP1, fbw1a, FBW1A, Fbw1a, fbxw1, FBXW1, fbxw1a, FBXW1A, fwd1, FWD1, HOS, mKIAA4123, SlimbBezeichner auf Proteinebene für BTRC
- beta-transducin repeat containing
- beta-transducin repeat containing protein
- F-box/WD repeat-containing protein 1A
- f-box/WD repeat-containing protein 1A-like
- E3RSIkappaB
- F-box and WD repeats protein beta-TrCP
- F-box and WD-repeat protein 1B
- beta-TrCP1
- epididymis tissue protein Li 2a
- pIkappaBalpha-E3 receptor subunit
- beta-TrCP
- beta-transducin repeat-containing protein
- SCF b-TRCP
- beta-TrCP protein E3RS-IkappaB
- mE3RS-IkappaB
- pIkappaB-E3 receptor subunit
- ubiquitin ligase FWD1
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