CAD Produkte
(Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD))
Kategorien
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. [provided by RefSeq, Jul 2008].
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Ausgewählte CAD Kategorien
CAD Antikörper
High quality antibodies with extensive validation data.
Empfohlene CAD Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p), FACS
Validierungen
- (7)
Kat. Nr.
ABIN655062
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
IHC, WB, IF
Validierungen
- (8)
Kat. Nr.
ABIN7264367
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
IHC, WB, IF
Validierungen
- (6)
Kat. Nr.
ABIN6137837
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene CAD Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7122124
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CAD Produkten
: "Identification of CAD as an androgen receptor interactant and an early marker of prostate tumor recurrence." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 26, Issue 1, pp. 460-7, (2012) (PubMed).: "Phospho-ΔNp63α/SREBF1 protein interactions: bridging cell metabolism and cisplatin chemoresistance." in: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 20, pp. 3810-27, (2012) (PubMed).
: "Expression of caspase-activated deoxyribonuclease (CAD) and caspase 3 (CPP32) in the cochlea of cisplatin (CDDP)-treated guinea pigs." in: Auris, nasus, larynx, Vol. 30, Issue 3, pp. 219-25, (2003) (PubMed).
: "Expression of caspase-activated deoxyribonuclease (CAD) and caspase 3 (CPP32) in the hydropic cochlea of guinea pigs - second report." in: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, Vol. 259, Issue 5, pp. 257-61, (2002) (PubMed).
: "Over expression of inhibitor of caspase 3 activated deoxyribonuclease in human renal cell carcinoma cells enhances their resistance to cytotoxic chemotherapy in vivo." in: The Journal of urology, Vol. 166, Issue 6, pp. 2491-4, (2001) (PubMed).
: "TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB." in: Immunity, Vol. 7, Issue 6, pp. 831-6, (1998) (PubMed).
Synonyme und alternative Namen zu CAD
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (CAD), carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (Cad), carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (cad), 2410008J01Rik, AU018859, CAD, cb456, Cpad, si:dkey-221h15.3, wu:fc30c12, wu:fc33d01, wu:fc67g02, xcadBezeichner auf Proteinebene für CAD
- CAD protein
- CAD trifunctional protein
- multifunctional protein CAD
- carbamyl phosphatate synthetase 2
- carbamoylphosphate synthetase 2/aspartate transcarbamylase/dihydroorotase
- carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
- CAD protein-like
- CAD protein carbamylphosphate synthetase domain
- dihydrorotate synthase
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