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Cadherin 4 Produkte

(Cadherin 4 (CDH4))
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].

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Ausgewählte Cadherin 4 Kategorien

Cadherin 4 Antikörper

High quality antibodies with extensive validation data.

Cadherin 4 ELISA Kits

Reliable ELISA kits for a wide range of species.

Cadherin 4 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Cadherin 4 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IF, FACS, IHC (p)
Validierungen
  • (1)
  • (5)
Kat. Nr. ABIN388148
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Mouse, Rat
Applikation WB, IHC, IP
Validierungen
  • (3)
  • (3)
Kat. Nr. ABIN967954
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF, FACS, IHC (p), EIA
Validierungen
  • (4)
Kat. Nr. ABIN356865
Menge 0.4 mL
Datenblatt Datenblatt

Empfohlene Cadherin 4 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6730333
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN4882287
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6385128
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Cadherin 4 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1348916
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7403762
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
Kat. Nr. ABIN7317950
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Cadherin 4 Produkten

Mills, Globa, Liu, Cowan, Mobasser, Phillips, Borgland, Bamji: "Cadherins mediate cocaine-induced synaptic plasticity and behavioral conditioning." in: Nature neuroscience, Vol. 20, Issue 4, pp. 540-549, (2017) (PubMed).

Cremaschi, Oliverio, Leva, Bione, Carriero, Mazzucco, Palamidessi, Scita, Biamonti, Montecucco: "Chronic Replication Problems Impact Cell Morphology and Adhesion of DNA Ligase I Defective Cells." in: PLoS ONE, Vol. 10, Issue 7, pp. e0130561, (2015) (PubMed).

Aschauer, Gruber, Pfaller, Limonciel, Athersuch, Cavill, Khan, Gstraunthaler, Grillari, Grillari, Hewitt, Leonard, Wilmes, Jennings: "Delineation of the key aspects in the regulation of epithelial monolayer formation." in: Molecular and cellular biology, Vol. 33, Issue 13, pp. 2535-50, (2013) (PubMed).

Li, Takai, Yuge, Furukawa, Tsuno, Tsukamoto, Kong, Moriyama, Narahara: "Novel target genes responsive to the anti-growth activity of triptolide in endometrial and ovarian cancer cells." in: Cancer letters, Vol. 297, Issue 2, pp. 198-206, (2010) (PubMed).

Johnson, Theisen, Johnson, Wheelock: "R-cadherin influences cell motility via Rho family GTPases." in: The Journal of biological chemistry, Vol. 279, Issue 30, pp. 31041-9, (2004) (PubMed).

Miotto, Sabbioni, Veronese, Calin, Gullini, Liboni, Gramantieri, Bolondi, Ferrazzi, Gafà, Lanza, Negrini: "Frequent aberrant methylation of the CDH4 gene promoter in human colorectal and gastric cancer." in: Cancer research, Vol. 64, Issue 22, pp. 8156-9, (2004) (PubMed).

Kitagawa, Natori, Murase, Hirano, Taketani, Suzuki: "Mutation analysis of cadherin-4 reveals amino acid residues of EC1 important for the structure and function." in: Biochemical and biophysical research communications, Vol. 271, Issue 2, pp. 358-63, (2000) (PubMed).

Tanihara, Sano, Heimark, St John, Suzuki: "Cloning of five human cadherins clarifies characteristic features of cadherin extracellular domain and provides further evidence for two structurally different types of cadherin." in: Cell adhesion and communication, Vol. 2, Issue 1, pp. 15-26, (1995) (PubMed).

Hutton, Christofori, Chi, Edman, Guest, Hanahan, Kelly: "Molecular cloning of mouse pancreatic islet R-cadherin: differential expression in endocrine and exocrine tissue." in: Molecular endocrinology (Baltimore, Md.), Vol. 7, Issue 9, pp. 1151-60, (1994) (PubMed).

Matsunami, Miyatani, Inoue, Copeland, Gilbert, Jenkins, Takeichi: "Cell binding specificity of mouse R-cadherin and chromosomal mapping of the gene." in: Journal of cell science, Vol. 106 ( Pt 1), Issue 6, pp. 401-9, (1994) (PubMed).

Synonyme und alternative Namen zu Cadherin 4

cadherin 4 (cdh4), cadherin 4 (Cdh4), cadherin 4, type 1, R-cadherin (retinal) (cdh4), cadherin 4 (CDH4), Cadherin-4 (cdh-4), AW120700, cad4, CAD4, cadherin-4, Cdh4l, R-Cadh, R-cadherin, rcad, Rcad, RCAD, zgc:136316

Bezeichner auf Proteinebene für Cadherin 4

  • cadherin 4, type 1, R-cadherin (retinal)
  • R-CAD
  • cadherin-4
  • retina cadherin
  • retinal cadherin
  • R-cadherin
  • cadherin 4 type 1 R-cadherin (retinal)
  • cadherin 4, type 1, preproprotein
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