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CARD11 Produkte

(Caspase Recruitment Domain Family, Member 11 (CARD11))

Kategorien

The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008].

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Ausgewählte CARD11 Kategorien

CARD11 Antikörper

High quality antibodies with extensive validation data.

CARD11 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene CARD11 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (5)
Kat. Nr. ABIN7266125
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation IHC, IF
Validierungen
  • (2)
Kat. Nr. ABIN7263125
Menge 200 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF, ICC
Validierungen
  • (2)
Kat. Nr. ABIN6260459
Menge 100 μL
Datenblatt Datenblatt

Empfohlene CARD11 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6202319
Menge 96 tests
Datenblatt Datenblatt

Empfohlene CARD11 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1348037
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3090358
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3136496
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CARD11 Produkten

Gu, Sun: "MiR-539 inhibits thyroid cancer cell migration and invasion by directly targeting CARMA1." in: Biochemical and biophysical research communications, Vol. 464, Issue 4, pp. 1128-33, (2015) (PubMed).

Cheng, Hamilton, Kane: "Phosphorylation of Carma1, but not Bcl10, by Akt regulates TCR/CD28-mediated NF-κB induction and cytokine production." in: Molecular immunology, Vol. 59, Issue 1, pp. 110-6, (2014) (PubMed).

Hamilton, Phong, Corey, Cheng, Gorentla, Zhong, Shiva, Kane: "T cell receptor-dependent activation of mTOR signaling in T cells is mediated by Carma1 and MALT1, but not Bcl10." in: Science signaling, Vol. 7, Issue 329, pp. ra55, (2014) (PubMed).

Rajasekaran, Kumar, Schuldt, Peterson, Vanhaesebroeck, Dixit, Thakar, Malarkannan: "Signaling by Fyn-ADAP via the Carma1-Bcl-10-MAP3K7 signalosome exclusively regulates inflammatory cytokine production in NK cells." in: Nature immunology, Vol. 14, Issue 11, pp. 1127-36, (2013) (PubMed).

Moreno-García, Sommer, Shinohara, Bandaranayake, Kurosaki, Rawlings: "MAGUK-controlled ubiquitination of CARMA1 modulates lymphocyte NF-kappaB activity." in: Molecular and cellular biology, Vol. 30, Issue 4, pp. 922-34, (2010) (PubMed).

Rueda, Gaide, Ho, Lewkowicz, Niedergang, Hailfinger, Rebeaud, Guzzardi, Conne, Thelen, Delon, Ferch, Mak, Ruland, Schwaller, Thome: "Bcl10 controls TCR- and FcgammaR-induced actin polymerization." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 7, pp. 4373-84, (2007) (PubMed).

Medeiros, Burbach, Mueller, Srivastava, Moon, Highfill, Peterson, Shimizu: "Regulation of NF-kappaB activation in T cells via association of the adapter proteins ADAP and CARMA1." in: Science (New York, N.Y.), Vol. 316, Issue 5825, pp. 754-8, (2007) (PubMed).

Ho, Davis, Conne, Chappuis, Berczy, Mhawech, Staudt, Schwaller: "MALT1 and the API2-MALT1 fusion act between CD40 and IKK and confer NF-kappa B-dependent proliferative advantage and resistance against FAS-induced cell death in B cells." in: Blood, Vol. 105, Issue 7, pp. 2891-9, (2005) (PubMed).

Sommer, Guo, Pomerantz, Bandaranayake, Moreno-García, Ovechkina, Rawlings: "Phosphorylation of the CARMA1 linker controls NF-kappaB activation." in: Immunity, Vol. 23, Issue 6, pp. 561-74, (2005) (PubMed).

Nakamura, Nakamura, Matsumoto, Yada, Hirahashi, Suekane, Yao, Goda, Iida: "Overexpression of caspase recruitment domain (CARD) membrane-associated guanylate kinase 1 (CARMA1) and CARD9 in primary gastric B-cell lymphoma." in: Cancer, Vol. 104, Issue 9, pp. 1885-93, (2005) (PubMed).

Synonyme und alternative Namen zu CARD11

caspase recruitment domain family member 11 (CARD11), caspase recruitment domain family, member 11 (Card11), caspase recruitment domain-containing protein 11 (LOC100550812), caspase recruitment domain family member 11 (card11), caspase recruitment domain family member 11 (Card11), 0610008L17Rik, 2410011D02Rik, BENTA, BIMP3, CARD11, CARMA1, LOC100232755, PPBL

Bezeichner auf Proteinebene für CARD11

  • CARD-containing MAGUK protein 1
  • bcl10-interacting maguk protein 3
  • carma 1
  • caspase recruitment domain-containing protein 11
  • caspase recruitment domain family, member 11
  • caspase recruitment domain-containing protein 11-like
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