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Caspase 1 Produkte

(Caspase 1 (CASP1))

Kategorien

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012].

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Ausgewählte Caspase 1 Kategorien

Caspase 1 Antikörper

High quality antibodies with extensive validation data.

Caspase 1 ELISA Kits

Reliable ELISA kits for a wide range of species.

Caspase 1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Caspase 1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (7)
Kat. Nr. ABIN7438055
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (7)
Kat. Nr. ABIN7433831
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Mouse
Applikation WB, IHC, IP, ICC
Validierungen
  • (8)
Kat. Nr. ABIN7437506
Menge 100 μL
Datenblatt Datenblatt

Empfohlene Caspase 1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (3)
  • (5)
Kat. Nr. ABIN6574284
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6954410
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6965449
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Caspase 1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7122160
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7122161
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1776262
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Caspase 1 Produkten

Lv, Liu, Ye, Yang, Duan, Yao, Li, Tang, Chen, Liu, Deng, Wang, Xing, Liang, Xu, Ye: "XIST Inhibition Attenuates Calcium Oxalate Nephrocalcinosis-Induced Renal Inflammation and Oxidative Injury via the miR-223/NLRP3 Pathway." in: Oxidative medicine and cellular longevity, Vol. 2021, pp. 1676152, (2022) (PubMed).

Wu, He, Li, Xu, Zhong, Bu, Huang: "Efficient and Consistent Orthotopic Osteosarcoma Model by Cell Sheet Transplantation in the Nude Mice for Drug Testing." in: Frontiers in bioengineering and biotechnology, Vol. 9, pp. 690409, (2021) (PubMed).

Zhou, Xiao, Zhao, Tan, Long, Yu, He: "Enhanced Autolysosomal Function Ameliorates the Inflammatory Response Mediated by the NLRP3 Inflammasome in Alzheimer's Disease." in: Frontiers in aging neuroscience, Vol. 13, pp. 629891, (2021) (PubMed).

Wang, Li, Peng, Hu, Rao, Li: "HMGB1 participates in LPS‑induced acute lung injury by activating the AIM2 inflammasome in macrophages and inducing polarization of M1 macrophages via TLR2, TLR4, and RAGE/NF‑κB signaling pathways." in: International journal of molecular medicine, Vol. 45, Issue 1, pp. 61-80, (2020) (PubMed).

Cabus, Kabukcu, Fenkci, Caner, Oztekin, Fenkci, Enli: "Serum Caspase-1 levels in women with polycystic ovary syndrome." in: Taiwanese journal of obstetrics & gynecology, Vol. 59, Issue 2, pp. 207-210, (2020) (PubMed).

Lopes de Oliveira, Alarcón de la Lastra, Rosillo, Castejon Martinez, Sánchez-Hidalgo, Rolim Medeiros, Villegas: "Preventive effect of bergenin against the development of TNBS-induced acute colitis in rats is associated with inflammatory mediators inhibition and NLRP3/ASC inflammasome signaling pathways." in: Chemico-biological interactions, Vol. 297, pp. 25-33, (2019) (PubMed).

Mandal, Feng, Lyons, Berger, Otani, DeLaney, Tharp, Maner-Smith, Burd, Schaeffer, Hoffman, Capriotti, Roback, Young, Liang, Ortlund, DiPaolo, Bosinger, Bertin, Gough, Brodsky, Coopersmith et al.: "Caspase-8 Collaborates with Caspase-11 to Drive Tissue Damage and Execution of Endotoxic Shock. ..." in: Immunity, Vol. 49, Issue 1, pp. 42-55.e6, (2019) (PubMed).

Liu, Mateer, Hsu, Goggins, Tay, Mathe, Fan, Neal, Bruce, Burns, Minahan, Maltby, Fricker, Foster, Wark, Hansbro, Keely: "Platelet activating factor receptor regulates colitis-induced pulmonary inflammation through the NLRP3 inflammasome." in: Mucosal immunology, Vol. 12, Issue 4, pp. 862-873, (2019) (PubMed).

Raval, Schatz, Bhattacharya, dAdesky, Rundek, Dietrich, Bramlett: "Whole Body Vibration Therapy after Ischemia Reduces Brain Damage in Reproductively Senescent Female Rats." in: International journal of molecular sciences, Vol. 19, Issue 9, (2019) (PubMed).

Pronin, Pham, An, Dvoriantchikova, Reshetnikova, Qiao, Kozhekbaeva, Reiser, Slepak, Shestopalov: "Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury." in: Frontiers in molecular neuroscience, Vol. 12, pp. 36, (2019) (PubMed).

Synonyme und alternative Namen zu Caspase 1

caspase 1 (CASP1), caspase 1 (Casp1), caspase 1, apoptosis-related cysteine peptidase (CASP1), caspase 4, apoptosis-related cysteine peptidase (CASP4), Death caspase-1 (Dcp-1), caspase-1 (Caspase1), caspase (LOC5564196), caspase recruitment domain-containing protein 16 (LOC451519), caspase-1 (CASP1), caspase 4 (CASP4), CASP1, ccp1, CG5370, DCP-1, dcp-1, DCP1, Dcp1, dcp1, Dmel\\CG5370, ICE, Ice, IL1BC, Il1bc, l(2)01862, l(2)02132, P45

Bezeichner auf Proteinebene für Caspase 1

  • CASP1 nirs variant 1
  • IL-1 beta-converting enzyme
  • IL1B-convertase
  • caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
  • caspase-1
  • interleukin 1, beta, convertase
  • interleukin 1-B converting enzyme
  • CASP-1
  • IL-1B converting enzyme
  • IL-1BC
  • interleukin 1 beta-converting enzyme
  • interleukin-1 beta convertase
  • interleukin-1 beta-converting enzyme
  • p45
  • Interleukin 1beta converting enzyme
  • caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase)
  • ICE
  • interleukin-1 beta converting enzyme
  • caspase-1/caspase-4 hybrid
  • CG5370-PA
  • Dcp-1-PA
  • caspase
  • caspase 1
  • death caspase-1
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