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Caspase 6 Produkte

(Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Kategorien

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. [provided by RefSeq, Jul 2008].

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Ausgewählte Caspase 6 Kategorien

Caspase 6 Antikörper

High quality antibodies with extensive validation data.

Caspase 6 ELISA Kits

Reliable ELISA kits for a wide range of species.

Caspase 6 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Caspase 6 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Cow
Applikation WB, IHC, ICC, IP
Validierungen
  • (6)
Kat. Nr. ABIN7437107
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Cow
Applikation WB, IHC, ICC, IP
Validierungen
  • (5)
Kat. Nr. ABIN7437551
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, ICC, FACS
Validierungen
  • (5)
Kat. Nr. ABIN7193443
Menge 100 μL
Datenblatt Datenblatt

Empfohlene Caspase 6 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6965470
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6954422
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1380107
Menge 2 x 96 tests
Datenblatt Datenblatt

Empfohlene Caspase 6 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1348111
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Cow
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7400309
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7396214
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Caspase 6 Produkten

Alegro, Theofilas, Nguy, Castruita, Seeley, Heinsen, Ushizima, Grinberg: "Automating cell detection and classification in human brain fluorescent microscopy images using dictionary learning and sparse coding." in: Journal of neuroscience methods, Vol. 282, pp. 20-33, (2017) (PubMed).

Zhou, Li, Tian, Wang, Ding, Pang: "Changes in phosphatidylinositol 3-kinase 55 kDa gamma expression and subcellular localization may be caspase 6 dependent in paraquat-induced SH-SY5Y apoptosis." in: Human & experimental toxicology, Vol. 33, Issue 7, pp. 761-71, (2015) (PubMed).

Berta, Park, Xu, Xie, Liu, Lü, Liu, Ji: "Extracellular caspase-6 drives murine inflammatory pain via microglial TNF-α secretion." in: The Journal of clinical investigation, Vol. 124, Issue 3, pp. 1173-86, (2014) (PubMed).

Saggar, Tannock: "Activity of the hypoxia-activated pro-drug TH-302 in hypoxic and perivascular regions of solid tumors and its potential to enhance therapeutic effects of chemotherapy." in: International journal of cancer, Vol. 134, Issue 11, pp. 2726-34, (2014) (PubMed).

Xia, Yang, Bu, Ji, Zhao, Zheng, Lin, Li, Lu: "Differential regulation of c-Jun protein plays an instrumental role in chemoresistance of cancer cells." in: The Journal of biological chemistry, Vol. 288, Issue 27, pp. 19321-9, (2013) (PubMed).

Saggar, Fung, Patel, Tannock: "Use of molecular biomarkers to quantify the spatial distribution of effects of anticancer drugs in solid tumors." in: Molecular cancer therapeutics, Vol. 12, Issue 4, pp. 542-52, (2013) (PubMed).

Yashiro, Qiu, Hasegawa, Zhang, Matsuzaki, Hirakawa: "An EGFR inhibitor enhances the efficacy of SN38, an active metabolite of irinotecan, in SN38-refractory gastric carcinoma cells." in: British journal of cancer, (2011) (PubMed).

Vohra, Sasaki, Miller, Chang, DiAntonio, Milbrandt: "Amyloid precursor protein cleavage-dependent and -independent axonal degeneration programs share a common nicotinamide mononucleotide adenylyltransferase 1-sensitive pathway." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 41, pp. 13729-38, (2010) (PubMed).

Kobayashi, Nolan, Naveed, Hoshino, Segal, Fujita, Rom, Weiden: "Neutrophils activate alveolar macrophages by producing caspase-6-mediated cleavage of IL-1 receptor-associated kinase-M." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 1, pp. 403-10, (2010) (PubMed).

Murakami, Tolstykh, Bao, Niu, Steuer, Bao, Chang, Espiritu, Bansal, Lam, Otto, Sofia, Furman: "Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34337-47, (2010) (PubMed).

Synonyme und alternative Namen zu Caspase 6

caspase 6 L homeolog (casp6.L), caspase 6 (casp6), caspase 6, apoptosis-related cysteine peptidase (casp6), group XIIA secretory phospholipase A2 (CASP6), caspase-6 (CpipJ_CPIJ017008), caspase 6 (Casp6), caspase 6 (CASP6), CASP6, casp6, caspase-6, mCASP-6, mch2, Mch2, MCH2, xCaspase-6, zgc:112960

Bezeichner auf Proteinebene für Caspase 6

  • caspase-6
  • caspase 6, apoptosis-related cysteine protease
  • caspase-6a
  • caspase 6
  • Caspase-6
  • CASP-6
  • apoptotic protease Mch-2
  • apoptotic protease MCH-2
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