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CASR Produkte

(Calcium-Sensing Receptor (CASR))

Kategorien

The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq, Jul 2008].

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Ausgewählte CASR Kategorien

CASR Antikörper

High quality antibodies with extensive validation data.

CASR ELISA Kits

Reliable ELISA kits for a wide range of species.

CASR Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene CASR Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN1678994
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IF, ICC
Validierungen
  • (4)
Kat. Nr. ABIN6255749
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Pig
Applikation WB, ELISA
Validierungen
  • (2)
  • (2)
Kat. Nr. ABIN1386858
Menge 100 μL
Datenblatt Datenblatt

Empfohlene CASR ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6954279
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6954278
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6954280
Menge 96 tests
Datenblatt Datenblatt

Empfohlene CASR Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1348127
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1348129
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7505157
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CASR Produkten

Issa, Hénaut, Abdallah, Boudot, Lenglet, Avondo, Ibrik, Caus, Brazier, Mentaverri, Zibara, Kamel: "Activation of the calcium-sensing receptor in human valvular interstitial cells promotes calcification." in: Journal of molecular and cellular cardiology, Vol. 129, pp. 2-12, (2019) (PubMed).

Luchsinger, Strikoudis, Danzl, Bush, Finlayson, Satwani, Sykes, Yazawa, Snoeck: "Harnessing Hematopoietic Stem Cell Low Intracellular Calcium Improves Their Maintenance In Vitro." in: Cell stem cell, Vol. 25, Issue 2, pp. 225-240.e7, (2019) (PubMed).

Bächinger, Egli, Goosmann, Monge Naldi, Eckhard: "Immunolocalization of calcium sensing and transport proteins in the murine endolymphatic sac indicates calciostatic functions within the inner ear." in: Cell and tissue research, (2019) (PubMed).

Liu, Tan, Huang, Li, Wang, Liao, Guan, Ji, Yin: "Involvement of calcium-sensing receptor activation in the alleviation of intestinal inflammation in a piglet model by dietary aromatic amino acid supplementation." in: The British journal of nutrition, Vol. 120, Issue 12, pp. 1321-1331, (2019) (PubMed).

Frees, Breuksch, Haber, Bauer, Chavez-Munoz, Raven, Moskalev, D Costa, Tan, Daugaard, Thüroff, Haferkamp, Prawitt, So, Brenner: "Calcium-sensing receptor (CaSR) promotes development of bone metastasis in renal cell carcinoma." in: Oncotarget, Vol. 9, Issue 21, pp. 15766-15779, (2018) (PubMed).

Yuan, Shi, Li, Yang, Tang, Hu, Du, Li, Gu, Wang, Xi, Tang: "Evaluation of a TPTX model induced by ischemia." in: Experimental animals, Vol. 66, Issue 4, pp. 345-356, (2018) (PubMed).

Boudot, Hénaut, Thiem, Geraci, Galante, Saldanha, Saidak, Six, Clézardin, Kamel, Mentaverri et al.: "Overexpression of a functional calcium-sensing receptor dramatically increases osteolytic potential of MDA-MB-231 cells in a mouse model of bone metastasis through epiregulin-mediated osteoprotegerin ..." in: Oncotarget, Vol. 8, Issue 34, pp. 56460-56472, (2017) (PubMed).

Yasukawa, Hayashi, Tanabe, Tsuda, Suzuki, Kawato, Suzuki, Maeno, Ogiso: "Involvement of the calcium-sensing receptor in mineral trioxide aggregate-induced osteogenic gene expression in murine MC3T3-E1 cells." in: Dental materials journal, Vol. 36, Issue 4, pp. 469-475, (2017) (PubMed).

Zeng, Zhu, Xiao, Liu, Sun, Liu, Hao, Lu, Zhang, Li, Wang, Wei, Hu: "Hypoxia-Induced Mitogenic Factor Acts as a Nonclassical Ligand of Calcium-Sensing Receptor, Therapeutically Exploitable for Intermittent Hypoxia-Induced Pulmonary Hypertension." in: Hypertension (Dallas, Tex. : 1979), Vol. 69, Issue 5, pp. 844-854, (2017) (PubMed).

Xiao, Su, Feng, Sun, Liu, Zhang, Lu, Li, Wang, Zhu, Hu: "Monocrotaline Induces Endothelial Injury and Pulmonary Hypertension by Targeting the Extracellular Calcium-Sensing Receptor." in: Journal of the American Heart Association, Vol. 6, Issue 4, (2017) (PubMed).

Synonyme und alternative Namen zu CASR

calcium sensing receptor (CASR), calcium-sensing receptor (Casr), calcium-sensing receptor L homeolog (casr.L), calcium sensing receptor (Casr), CAR, CaR, CASR, EIG8, FHH, FIH, GPRC2A, Gprc2a, gprc2a, HHC, HHC1, HYPOC1, NSHPT, PCAR1, xV2R F-1

Bezeichner auf Proteinebene für CASR

  • extracellular calcium-sensing receptor
  • parathyroid Ca(2+)-sensing receptor 1
  • parathyroid cell calcium-sensing receptor
  • G protein coupled receptor, family C, group 2, member A
  • G protein-coupled receptor, family C, group 2, member A
  • PCaR1
  • cation sensing receptor
  • Calcium-sensing receptor (hypocalciuric hypercalcemia 1 severe neonatal hyperparathyroidism)
  • Calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism)
  • parathyroid Cell calcium-sensing receptor
  • calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism)
  • calcium-sensing receptor
  • vomeronasal receptor F-1
  • parathyroid gland calcium-sensing receptor
  • extracellular calcium-sensing receptor-like
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