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C-Type Lectin Domain Family 4, Member M Proteine

(C-Type Lectin Domain Family 4, Member M (CLEC4M))

This gene encodes a transmembrane receptor and is often referred to as L-SIGN because of its expression in the endothelial cells of the lymph nodes and liver. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses, with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are common and have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene (GeneID 30835\; often referred to as DC-SIGN or CD209). DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution. Alternative splicing results in multiple variants.[provided by RefSeq, Feb 2009].

Empfehlung

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 285-394) protein (GST tag) (ABIN1349664)

CLEC4M Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP

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Empfehlung

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 71-399) protein (His-DYKDDDDK Tag) (ABIN7504305)

CLEC4M Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC

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Empfehlung

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 71-399) Protein (ABIN7504304)

CLEC4M Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

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C-Type Lectin Domain Family 4, Member M Proteine nach Origin

Hier sind C-Type Lectin Domain Family 4, Member M Proteine für eine Vielzahl von Species wie anti-Human C-Type Lectin Domain Family 4, Member M, anti-Chimpanzee C-Type Lectin Domain Family 4, Member M zu finden. Die unten aufgeführten Species gehören zu den verfügbaren Arten. Klicken Sie auf einen Link, um zu den entsprechenden Produkten zu gelangen.

C-Type Lectin Domain Family 4, Member M Proteine nach Source

Hier finden Sie C-Type Lectin Domain Family 4, Member M Proteine Proteine, die nach mehreren wichtigen Quellen organisiert sind. Durch Anklicken eines Links können Sie auf die Produkte zugreifen. Für zusätzliche Quellen nutzen Sie bitte unsere Suchfunktion.

C-Type Lectin Domain Family 4, Member M Proteine nach Protein-Typ

Hier können Sie C-Type Lectin Domain Family 4, Member M Proteine Proteine finden, die nach verfügbaren Proteintypen kategorisiert sind. Zusätzliche Proteintypen können mit unserer Suchfunktion gefunden werden.

C-Type Lectin Domain Family 4, Member M Proteine nach Anwendung

Hier sind C-Type Lectin Domain Family 4, Member M Proteine zu finden, welche für eine bestimmte Anwendung wie ELISA, WB, AbP, SDS validiert wurde. Einige der verfügbaren Anwendungen sind unten aufgeführt. Klicken Sie auf einen Link, um zu den entsprechenden Produkten zu gelangen.

Häufig verwendete C-Type Lectin Domain Family 4, Member M Proteine

Produkt

Reaktivität

Source

Validierungen

Kat. Nr.

Menge

Datenblatt

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 285-394) protein (GST tag)

Reaktivität Human

Source Wheat germ

Validierungen

Kat. Nr. ABIN1349664

Menge 10 μg

Datenblatt Datenblatt

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 71-399) protein (His-DYKDDDDK Tag)

Reaktivität Human

Source HEK-293 Cells

Validierungen

Kat. Nr. ABIN7504305

Menge 100 μg

Datenblatt Datenblatt

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 71-399) Protein

Reaktivität Human

Source HEK-293 Cells

Validierungen

Kat. Nr. ABIN7504304

Menge 100 μg

Datenblatt Datenblatt

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 242-399) protein (His tag)

Reaktivität Human

Source Escherichia coli (E. coli)

Validierungen

Kat. Nr. ABIN7413766

Menge 100 μg

Datenblatt Datenblatt

C-Type Lectin Domain Family 4, Member M (CLEC4M) protein (Fc Tag)

Reaktivität Human

Source HEK-293 Cells

Validierungen

Kat. Nr. ABIN7194490

Menge 100 μg

Datenblatt Datenblatt

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 1-399) protein (Strep Tag)

Reaktivität Human

Source Tobacco (Nicotiana tabacum)

Validierungen

Kat. Nr. ABIN3118083

Menge 1 mg

Datenblatt Datenblatt

C-Type Lectin Domain Family 4, Member M (CLEC4M) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)

Reaktivität Human

Source HEK-293 Cells

Validierungen

Kat. Nr. ABIN2716811

Menge 20 μg

Datenblatt Datenblatt

C-Type Lectin Domain Family 4, Member M (CLEC4M) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)

Reaktivität Human

Source HEK-293 Cells

Validierungen

Kat. Nr. ABIN2713616

Menge 20 μg

Datenblatt Datenblatt

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 71-445) protein (His tag)

Reaktivität Chimpanzee

Source Yeast

Validierungen

Kat. Nr. ABIN1636713

Menge 1 mg

Datenblatt Datenblatt

Aliase für C-Type Lectin Domain Family 4, Member M Proteine

C-type lectin domain family 4 member M (CLEC4M) Proteine
CD209B Proteine
CD209L Proteine
CD299 Proteine
DC-SIGN2 Proteine
DC-SIGNR Proteine
DCSIGNR Proteine
HP10347 Proteine
L-SIGN Proteine
LSIGN Proteine

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C-Type Lectin Domain Family 4, Member M Proteine nach Origin

C-Type Lectin Domain Family 4, Member M Proteine nach Source

C-Type Lectin Domain Family 4, Member M Proteine nach Protein-Typ

C-Type Lectin Domain Family 4, Member M Proteine nach Anwendung

Häufig verwendete C-Type Lectin Domain Family 4, Member M Proteine

Aliase für C-Type Lectin Domain Family 4, Member M Proteine

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