C4A Produkte
(Complement Fragment C4a (C4a))
Kategorien
This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].
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Ausgewählte C4A Kategorien
C4A Antikörper
High quality antibodies with extensive validation data.
C4A ELISA Kits
Reliable ELISA kits for a wide range of species.
C4A Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene C4A Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
IHC, ELISA, Coat, StM
Validierungen
- (4)
Kat. Nr.
ABIN6940808
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (3)
Kat. Nr.
ABIN7440377
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (2)
Kat. Nr.
ABIN7431716
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene C4A ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (6)
- (1)
Kat. Nr.
ABIN6955046
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966053
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966051
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene C4A Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7122475
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1347536
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Rat
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7505492
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren C4A Produkten
: "Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment." in: Translational psychiatry, Vol. 7, Issue 5, pp. e1120, (2018) (PubMed).: "Quantitative analysis of hydroxyapatite-binding plasma proteins in genotyped individuals with late-stage age-related macular degeneration." in: Experimental eye research, Vol. 172, pp. 21-29, (2018) (PubMed).
: "Mechanisms of basin-scale nitrogen load reductions under intensified irrigated agriculture." in: PLoS ONE, Vol. 10, Issue 3, pp. e0120015, (2015) (PubMed).
: "Novel Photoresponsive Linear, Graft, and Comb-Like Copolymers with Azobenzene Chromophores in the Main-Chain and/or Side-Chain: Facile One-Pot Synthesis and Photoresponse Properties." in: Macromolecular rapid communications, Vol. 36, Issue 17, pp. 1578-84, (2015) (PubMed).
: "Identification of altered plasma proteins by proteomic study in valvular heart diseases and the potential clinical significance." in: PLoS ONE, Vol. 8, Issue 8, pp. e72111, (2013) (PubMed).
: "Circulation levels of acute phase proteins in patients with Takayasu arteritis." in: Journal of vascular surgery, Vol. 51, Issue 3, pp. 700-6, (2010) (PubMed).
: "Alternative complement activity in the egg cytosol of amphioxus Branchiostoma belcheri: evidence for the defense role of maternal complement components." in: PLoS ONE, Vol. 4, Issue 1, pp. e4234, (2009) (PubMed).
: "Complement activity in the egg cytosol of zebrafish Danio rerio: evidence for the defense role of maternal complement components." in: PLoS ONE, Vol. 3, Issue 1, pp. e1463, (2008) (PubMed).
: "Plasma C3a and C4a levels in liver transplant recipients: a longitudinal study." in: Immunopharmacology, Vol. 46, Issue 2, pp. 163-74, (2000) (PubMed).
: "Possible mechanism for in vitro complement activation in blood and plasma samples: futhan/EDTA controls in vitro complement activation." in: Clinical chemistry, Vol. 45, Issue 8 Pt 1, pp. 1190-9, (1999) (PubMed).
Synonyme und alternative Namen zu C4A
complement C4A (Rodgers blood group) (C4A), complement component 4A (Rodgers blood group) (C4a), C4, C4-1, C4A2, C4A3, C4A4, C4A6, C4AD, C4b, C4S, CO4, CPAMD2, RG, SlpBezeichner auf Proteinebene für C4A
- C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2
- C4A anaphylatoxin
- Rodgers form of C4
- acidic C4
- acidic complement C4
- complement C4-A
- sex-limited protein
- complement C4
- complement component 4 (within H-2S)
- complement component 4, gene 1
- complement component 4B (Chido blood group)
- complement component 4B (Childo blood group)
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