C4BP Produkte
(C4b-Binding Protein)
Kategorien
This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq, Jul 2008].
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Empfohlene C4BP Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ID, IHC (p)
Validierungen
- (2)
Kat. Nr.
ABIN957838
Menge
1 mL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, WB
Validierungen
Kat. Nr.
ABIN6976361
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene C4BP Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Human
Validierungen
Kat. Nr.
ABIN3119630
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren C4BP Produkten
: "Biofilm formation avoids complement immunity and phagocytosis of Streptococcus pneumoniae." in: Infection and immunity, Vol. 81, Issue 7, pp. 2606-15, (2013) (PubMed).: "Functions of human complement inhibitor C4b-binding protein in relation to its structure." in: Archivum immunologiae et therapiae experimentalis, Vol. 52, Issue 2, pp. 83-95, (2004) (PubMed).
Synonyme und alternative Namen zu C4BP
complement component 4 binding protein (C4bp), complement component 4 binding protein beta (C4BPB), AI195242, C4BP, C4bpaBezeichner auf Proteinebene für C4BP
- C4b-binding protein
- C4b-binding protein beta chain
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