CBP Produkte
(CREB Binding Protein (CREBBP))
Kategorien
This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving this gene have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2009].
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Ausgewählte CBP Kategorien
CBP Antikörper
High quality antibodies with extensive validation data.
CBP ELISA Kits
Reliable ELISA kits for a wide range of species.
CBP Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CBP Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IP, IHC (p), ICC, ChIP
Validierungen
- (1)
- (9)
- (1)
Kat. Nr.
ABIN2854987
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC, ELISA, IF, ICC
Validierungen
- (5)
Kat. Nr.
ABIN6260516
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, PLA
Validierungen
- (4)
Kat. Nr.
ABIN560465
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene CBP ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955103
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955104
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1381381
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene CBP Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7122497
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1350309
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (2)
Kat. Nr.
ABIN2669638
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CBP Produkten
: "A new cut&run low volume-urea (LoV-U) protocol optimized for transcriptional co-factors uncovers Wnt/b-catenin tissue-specific genomic targets." in: Development (Cambridge, England), (2022) (PubMed).: "Enriched environment modulates behavior, myelination and augments molecules governing the plasticity in the forebrain region of rats exposed to chronic immobilization stress." in: Metabolic brain disease, Vol. 34, Issue 3, pp. 875-887, (2020) (PubMed).
: "DYRK1A interacts with histone acetyl transferase p300 and CBP and localizes to enhancers." in: Nucleic acids research, (2018) (PubMed).
: "Tamoxifen Resistance in Breast Cancer Is Regulated by the EZH2-ERα-GREB1 Transcriptional Axis." in: Cancer research, Vol. 78, Issue 3, pp. 671-684, (2017) (PubMed).
: "Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. ..." in: Nature genetics, Vol. 44, Issue 10, pp. 1104-10, (2012) (PubMed).
: "Protein aggregation in motor neurone disorders." in: Neuropathology and applied neurobiology, Vol. 29, Issue 6, pp. 529-45, (2003) (PubMed).
Synonyme und alternative Namen zu CBP
CREB binding protein (CREBBP), CREB binding protein (Crebbp), CREB binding protein L homeolog (crebbp.L), histone acetyltransferase p300 (LOC100123220), AW558298, CBP, cbp, CBP/p300, crebbp, hmm291030, KAT3A, kat3a, Nejire, p300/CBP, RSTS, rsts, RTSBezeichner auf Proteinebene für CBP
- CREB-binding protein
- CREB binding protein (Rubinstein-Taybi syndrome)
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