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CBX1 Produkte

(Chromobox Homolog 1 (CBX1))

Kategorien

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].

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Ausgewählte CBX1 Kategorien

CBX1 Antikörper

High quality antibodies with extensive validation data.

CBX1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene CBX1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, IHC, FACS, ICC
Validierungen
  • (8)
Kat. Nr. ABIN5542477
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IF, IHC (p), ICC
Validierungen
  • (5)
Kat. Nr. ABIN2856369
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF
Validierungen
  • (4)
Kat. Nr. ABIN524353
Menge 100 μg
Datenblatt Datenblatt

Empfohlene CBX1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6211808
Menge 96 tests
Datenblatt Datenblatt

Empfohlene CBX1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN667490
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1348203
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1348201
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CBX1 Produkten

Boros, Arnoult, Stroobant, Collet, Decottignies: "Polycomb repressive complex 2 and H3K27me3 cooperate with H3K9 methylation to maintain heterochromatin protein 1? at chromatin." in: Molecular and cellular biology, Vol. 34, Issue 19, pp. 3662-74, (2014) (PubMed).

Leshner, Wang, Lewis, Zheng, Chen, Santy, Wang: "PAD4 mediated histone hypercitrullination induces heterochromatin decondensation and chromatin unfolding to form neutrophil extracellular trap-like structures." in: Frontiers in immunology, Vol. 3, pp. 307, (2012) (PubMed).

Ayoub, Jeyasekharan, Bernal, Venkitaraman: "HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response." in: Nature, Vol. 453, Issue 7195, pp. 682-6, (2008) (PubMed).

Lomberk, Wallrath, Urrutia: "The Heterochromatin Protein 1 family." in: Genome biology, Vol. 7, Issue 7, pp. 228, (2007) (PubMed).

Wang, Koyama, Nishida, Haraguchi, Reith, Tsukamoto: "The assembly and maintenance of heterochromatin initiated by transgene repeats are independent of the RNA interference pathway in mammalian cells." in: Molecular and cellular biology, Vol. 26, Issue 11, pp. 4028-40, (2006) (PubMed).

Stelzl, Worm, Lalowski, Haenig, Brembeck, Goehler, Stroedicke, Zenkner, Schoenherr, Koeppen, Timm, Mintzlaff, Abraham, Bock, Kietzmann, Goedde, Toksöz, Droege, Krobitsch, Korn, Birchmeier, Lehrach et al.: "A human protein-protein interaction network: a resource for annotating the proteome. ..." in: Cell, Vol. 122, Issue 6, pp. 957-68, (2005) (PubMed).

Sharma, Hwang, Pandita, Gupta, Dhar, Parenteau, Agarwal, Worman, Wellinger, Pandita: "Human heterochromatin protein 1 isoforms HP1(Hsalpha) and HP1(Hsbeta) interfere with hTERT-telomere interactions and correlate with changes in cell growth and response to ionizing radiation." in: Molecular and cellular biology, Vol. 23, Issue 22, pp. 8363-76, (2003) (PubMed).

Kametaka, Takagi, Hayakawa, Haraguchi, Hiraoka, Yoneda: "Interaction of the chromatin compaction-inducing domain (LR domain) of Ki-67 antigen with HP1 proteins." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 7, Issue 12, pp. 1231-42, (2002) (PubMed).

Synonyme und alternative Namen zu CBX1

chromobox 1 (CBX1), chromobox 1 (Cbx1), chromobox homolog 1a (HP1 beta homolog Drosophila) (cbx1a), chromobox 1 S homeolog (cbx1.S), chromobox homolog 1b (HP1 beta homolog Drosophila) (cbx1b), CBX, Cbx, Cbx-rs2, cbx1, E430007M08Rik, HP1-BETA, HP1B, Hp1beta, HP1Hs-beta, HP1Hsbeta, M31, MOD1, p25beta, wu:fe14b09, zgc:55739, zgc:86924

Bezeichner auf Proteinebene für CBX1

  • HP1 beta homolog
  • chromobox homolog 1 (HP1 beta homolog Drosophila )
  • chromobox protein homolog 1
  • heterochromatin protein 1 homolog beta
  • heterochromatin protein 1-beta
  • heterochromatin protein p25 beta
  • modifier 1 protein
  • HP1 beta
  • chromobox homolog 1
  • heterochromatin protein p25
  • chromobox homolog 1 (HP1 beta homolog)
  • chromobox-like protein 1
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