CBX4 Produkte
(Chromobox Homolog 4 (CBX4))
Kategorien
E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones\; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
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Ausgewählte CBX4 Kategorien
CBX4 Antikörper
High quality antibodies with extensive validation data.
CBX4 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CBX4 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, FACS
Validierungen
- (6)
Kat. Nr.
ABIN5542423
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7150950
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC (p)
Validierungen
- (2)
- (2)
Kat. Nr.
ABIN389086
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene CBX4 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6209563
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene CBX4 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1348212
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3091174
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3131894
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CBX4 Produkten
: "HIF-1α SUMOylation affects the stability and transcriptional activity of HIF-1α in human lens epithelial cells." in: Graefe's archive for clinical and experimental ophthalmology, Vol. 253, Issue 8, pp. 1279-90, (2015) (PubMed).: "Oxidative stress-induced p53 activity is enhanced by a redox-sensitive TP53INP1 SUMOylation." in: Cell death and differentiation, Vol. 21, Issue 7, pp. 1107-18, (2014) (PubMed).
: "Contribution of CBX4 to cumulus oophorus cell phenotype in mice and attendant effects in cumulus cell cloned embryos." in: Physiological genomics, Vol. 46, Issue 2, pp. 66-80, (2014) (PubMed).
: "CBX4-mediated SUMO modification regulates BMI1 recruitment at sites of DNA damage." in: Nucleic acids research, Vol. 40, Issue 12, pp. 5497-510, (2012) (PubMed).
: "Human Polycomb protein 2 promotes ?-synuclein aggregate formation through covalent SUMOylation." in: Brain research, Vol. 1381, pp. 78-89, (2011) (PubMed).
: "The SUMO E3 ligase activity of Pc2 is coordinated through a SUMO interaction motif." in: Molecular and cellular biology, Vol. 30, Issue 9, pp. 2193-205, (2010) (PubMed).
: "Different polycomb group CBX family proteins associate with distinct regions of chromatin using nonhomologous protein sequences." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 43, pp. 16572-7, (2008) (PubMed).
: "Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesterone." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 44, pp. 16272-7, (2006) (PubMed).
: "The polycomb protein Pc2 is a SUMO E3." in: Cell, Vol. 113, Issue 1, pp. 127-37, (2003) (PubMed).
Synonyme und alternative Namen zu CBX4
chromobox 4 (CBX4), chromobox 4 (Cbx4), chromobox 4 S homeolog (cbx4.S), chromobox homolog 4 (CBX4), chromobox homolog 4 (Pc class homolog, Drosophila) (cbx4), cbx4-a, im:6911625, MPc2, NBP16, PC2, XPolycomb, zgc:158588Bezeichner auf Proteinebene für CBX4
- chromobox homolog 4
- E3 SUMO-protein ligase CBX4
- chromobox protein homolog 4
- polycomb 2 homolog
- NS5ATP1-binding protein 16
- Pc class 2 homolog
- chromobox homolog 4 (Pc class homolog, Drosophila)
- chromobox homolog 4 (Pc class homolog)
- chromobox homolog 4 (Polycomb)
- chromobox protein (CHCB3)
- chromobox-like protein 4
- polycomb 2
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