CCR5 Produkte
(Chemokine (C-C Motif) Receptor 5 (CCR5))
Kategorien
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte CCR5 Kategorien
CCR5 Antikörper
High quality antibodies with extensive validation data.
CCR5 ELISA Kits
Reliable ELISA kits for a wide range of species.
CCR5 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CCR5 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, FACS, IHC
Validierungen
- (7)
Kat. Nr.
ABIN5611203
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
IHC (fro)
Validierungen
- (6)
Kat. Nr.
ABIN6939154
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC (p)
Validierungen
- (1)
- (6)
Kat. Nr.
ABIN3044318
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene CCR5 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN6954650
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965712
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965711
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene CCR5 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7491564
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1348499
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN6964239
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CCR5 Produkten
: "Hippocampal CCR5/RANTES Elevations in a Rodent Model of Post-Traumatic Stress Disorder: Maraviroc (a CCR5 Antagonist) Increases Corticosterone Levels and Enhances Fear Memory Consolidation." in: Biomolecules, Vol. 10, Issue 2, (2020) (PubMed).: "Methamphetamine abuse affects gene expression in brain-derived microglia of SIV-infected macaques to enhance inflammation and promote virus targets." in: BMC immunology, Vol. 17, Issue 1, pp. 7, (2016) (PubMed).
: "CIB1 and CIB2 are HIV-1 helper factors involved in viral entry." in: Scientific reports, Vol. 6, pp. 30927, (2016) (PubMed).
: "Structural Insights into the Inhibitory Mechanism of an Antibody against B7-H6, a Stress-Induced Cellular Ligand for the Natural Killer Cell Receptor NKp30." in: Journal of molecular biology, Vol. 428, Issue 22, pp. 4457-4466, (2016) (PubMed).
: "Serum concentrations of chemokines (CCL-5 and CXCL-12), chemokine receptors (CCR-5 and CXCR-4), and IL-6 in patients with posttraumatic stress disorder and avoidant personality disorder." in: Pharmacological reports : PR, Vol. 67, Issue 6, pp. 1251-8, (2015) (PubMed).
: "A Linear Epitope in the N-Terminal Domain of CCR5 and Its Interaction with Antibody." in: PLoS ONE, Vol. 10, Issue 6, pp. e0128381, (2015) (PubMed).
: "CXCR4 expression on pathogenic T cells facilitates their bone marrow infiltration in a mouse model of aplastic anemia." in: Blood, Vol. 125, Issue 13, pp. 2087-94, (2015) (PubMed).
: "The effects of CCR5 inhibition on regulatory T-cell recruitment to colorectal cancer." in: British journal of cancer, Vol. 112, Issue 2, pp. 319-28, (2015) (PubMed).
: "Comparison of chemokines (CCL-5 and SDF-1), chemokine receptors (CCR-5 and CXCR-4) and IL-6 levels in patients with different severities of depression." in: Pharmacological reports : PR, Vol. 66, Issue 5, pp. 920-6, (2014) (PubMed).
: "CCR5 receptor antagonists block metastasis to bone of v-Src oncogene-transformed metastatic prostate cancer cell lines." in: Cancer research, Vol. 74, Issue 23, pp. 7103-14, (2014) (PubMed).
Synonyme und alternative Namen zu CCR5
C-C motif chemokine receptor 5 (gene/pseudogene) (CCR5), chemokine (C-C motif) receptor 5 (Ccr5), chemokine (C-C motif) receptor 5 (CCR5), C-C motif chemokine receptor 5 (CCR5), AM4-7, CC-CKR-5, CCCKR5, CCR-5, CCR1-L, CCR5, CD195, CKR-5, CKR5, Ckr5, CMKBR5, Cmkbr5, GPCR, IDDM22Bezeichner auf Proteinebene für CCR5
- C-C chemokine receptor type 5
- C-C motif chemokine receptor 5 A159A
- HIV-1 fusion coreceptor
- chemokine receptor CCR5
- chemr13
- C-C CKR-5
- CC-CKR-5
- CCR-5
- MIP-1 alpha receptor
- chemokine (C-C) receptor 5
- chemokine C-C motif receptor 5
- C-C chemokine receptor 11 like
- CC chemokine receptor 5
- chemokine receptor 5
- CC chemokine receptor type 5
- C-C chemokine receptor 5
- chemokine (C-C motif) receptor 5
- C-C chemokine receptor type 5-like
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