CD22 Produkte
(CD22 Molecule (CD22))
Kategorien
Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins\; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
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Ausgewählte CD22 Kategorien
CD22 Antikörper
High quality antibodies with extensive validation data.
CD22 ELISA Kits
Reliable ELISA kits for a wide range of species.
CD22 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CD22 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
FACS, WB, ELISA, IHC, ICC
Validierungen
- (2)
- (8)
Kat. Nr.
ABIN1724888
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
FACS, ELISA, ICC
Validierungen
- (2)
- (5)
Kat. Nr.
ABIN1724887
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
FACS, WB, ELISA, IHC, IF, Coat, StM
Validierungen
- (8)
Kat. Nr.
ABIN6941120
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene CD22 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965550
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6954499
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN1889443
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene CD22 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (4)
Kat. Nr.
ABIN7275595
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7275587
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7275606
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CD22 Produkten
: "The red blood cell as a novel regulator of human B-cell activation." in: Immunology, Vol. 163, Issue 4, pp. 436-447, (2021) (PubMed).: "Ischemia Reperfusion Injury Triggers CXCL13 Release and B-Cell Recruitment After Allogenic Kidney Transplantation." in: Frontiers in immunology, Vol. 11, pp. 1204, (2020) (PubMed).
: "Deep Mining of Complex Antibody Phage Pools Generated by Cell Panning Enables Discovery of Rare Antibodies Binding New Targets and Epitopes." in: Frontiers in pharmacology, Vol. 10, pp. 847, (2019) (PubMed).
: "Chimeric antigen receptors that trigger phagocytosis." in: eLife, Vol. 7, (2018) (PubMed).
: "The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-β1 production and FcRL4 expression." in: Nature immunology, Vol. 14, Issue 12, pp. 1256-65, (2013) (PubMed).
: "S100+ cells: a new neuro-immune cross-talkers in lymph organs." in: Scientific reports, Vol. 3, pp. 1114, (2013) (PubMed).
: "CD22 antigen is broadly expressed on lung cancer cells and is a target for antibody-based therapy." in: Cancer research, Vol. 72, Issue 21, pp. 5556-65, (2012) (PubMed).
: "CD22 regulates adaptive and innate immune responses of B cells." in: Journal of innate immunity, Vol. 3, Issue 4, pp. 411-9, (2011) (PubMed).
: "TRAIL and DR5 promote thyroid follicular cell apoptosis in iodine excess-induced experimental autoimmune thyroiditis in NOD mice." in: Biological trace element research, Vol. 143, Issue 2, pp. 1064-76, (2011) (PubMed).
: "Peripheral B cell tolerance and function in transgenic mice expressing an IgD superantigen." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 8, pp. 4143-58, (2010) (PubMed).
Synonyme und alternative Namen zu CD22
CD22 antigen (Cd22), CD22 molecule (CD22), CD22 molecule (Cd22), A530093D23, Lyb-8, Lyb8, SIGLEC-2, siglec-2, SIGLEC2Bezeichner auf Proteinebene für CD22
- B-cell receptor CD22
- B-lymphocyte cell adhesion molecule
- BL-CAM
- T-cell surface antigen Leu-14
- sialic acid-binding Ig-like lectin 2
- siglec-2
- CD22 antigen
- sialic acid binding Ig-like lectin 2
- Sialic acid-binding Ig-like lectin 2
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