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CD276 Produkte

(CD276)
The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].

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Ausgewählte CD276 Kategorien

CD276 Antikörper

High quality antibodies with extensive validation data.

CD276 ELISA Kits

Reliable ELISA kits for a wide range of species.

CD276 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene CD276 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, FACS, IHC, ICC
Validierungen
  • (6)
Kat. Nr. ABIN5611271
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (5)
Kat. Nr. ABIN7432586
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, FACS, IHC (p), IF
Validierungen
  • (5)
Kat. Nr. ABIN656709
Menge 400 μL
Datenblatt Datenblatt

Empfohlene CD276 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6954503
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6975125
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6951401
Menge 96 tests
Datenblatt Datenblatt

Empfohlene CD276 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7273951
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7273959
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Cynomolgus
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7273948
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CD276 Produkten

Wang, Ma, Zhan, Zhang, Cao, Zhang, Shi, Chen: "B7-H3 promotes colorectal cancer angiogenesis through activating the NF-κB pathway to induce VEGFA expression." in: Cell death & disease, Vol. 11, Issue 1, pp. 55, (2020) (PubMed).

Stern, Lown, Kobe, Abou-Elkacem, Willmann, Hackel: "Cellular-Based Selections Aid Yeast-Display Discovery of Genuine Cell-Binding Ligands: Targeting Oncology Vascular Biomarker CD276." in: ACS combinatorial science, Vol. 21, Issue 3, pp. 207-222, (2020) (PubMed).

Du, Hirabayashi, Ahn, Kren, Montgomery, Wang, Tiruthani, Mirlekar, Michaud, Greene, Herrera, Xu, Sun, Chen, Ma, Ferrone, Pylayeva-Gupta, Yeh, Liu, Savoldo, Ferrone, Dotti: "Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells." in: Cancer cell, Vol. 35, Issue 2, pp. 221-237.e8, (2019) (PubMed).

Gong, Kiyotani, Sakata, Nagano, Kumehara, Baba, Besse, Yanagitani, Friboulet, Nishio, Takeuchi, Kawamoto, Fujita, Katayama: "Secreted PD-L1 variants mediate resistance to PD-L1 blockade therapy in non-small cell lung cancer." in: The Journal of experimental medicine, Vol. 216, Issue 4, pp. 982-1000, (2019) (PubMed).

Zhang, Wang, Marzese, Wang, Yang, Li, Zhang, Zhang, Chen, Kelly, Hua, Hoon, Mao: "B7H3 regulates differentiation and serves as a potential biomarker and theranostic target for human glioblastoma." in: Laboratory investigation; a journal of technical methods and pathology, (2019) (PubMed).

Shi, Ma, Cao, Zhan, Xu, Fu, Liu, Zhang, Wang, Wang, Lu, Lu, Chen, Zhang: "B7-H3 promotes aerobic glycolysis and chemoresistance in colorectal cancer cells by regulating HK2." in: Cell death & disease, Vol. 10, Issue 4, pp. 308, (2019) (PubMed).

Wilson, Bachawal, Abou-Elkacem, Jensen, Machtaler, Tian, Willmann: "Spectroscopic Photoacoustic Molecular Imaging of Breast Cancer using a B7-H3-targeted ICG Contrast Agent." in: Theranostics, Vol. 7, Issue 6, pp. 1463-1476, (2018) (PubMed).

Hock, MacPherson, McKenzie: "Idelalisib and caffeine reduce suppression of T cell responses mediated by activated chronic lymphocytic leukemia cells." in: PLoS ONE, Vol. 12, Issue 3, pp. e0172858, (2017) (PubMed).

Li, Guo, Song, Cai, Yang, Chen, Wang, Huang, Gao: "B7-H3 Promotes the Migration and Invasion of Human Bladder Cancer Cells via the PI3K/Akt/STAT3 Signaling Pathway." in: Journal of Cancer, Vol. 8, Issue 5, pp. 816-824, (2017) (PubMed).

Quandt, Fiedler, Müller, Marsch, Seliger: "High constitutive B7-H3 expression on human keratinocytes supports T cell immunity." in: Journal of dermatological science, Vol. 87, Issue 1, pp. 82-85, (2017) (PubMed).

Synonyme und alternative Namen zu CD276

CD276 molecule (CD276), CD276 molecule S homeolog (cd276.S), CD276 molecule (cd276), CD276 antigen (Cd276), Cd276 molecule (Cd276), 4Ig-B7-H3, 6030411F23Rik, AU016588, B7-H3, B7h3, B7H3, B7RP-2, sc:d0645, zgc:158279

Bezeichner auf Proteinebene für CD276

  • CD276 molecule
  • CD276 antigen-like
  • CD276 antigen homolog
  • CD276 antigen
  • B7 homolog 3
  • B7-H3
  • costimulatory molecule
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