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CD33 Produkte

(CD33)

Kategorien

Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).

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Ausgewählte CD33 Kategorien

CD33 Antikörper

High quality antibodies with extensive validation data.

CD33 ELISA Kits

Reliable ELISA kits for a wide range of species.

CD33 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene CD33 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Applikation FACS, WB, ELISA, IHC (fro), IF (p), IF (cc), ICC, IHC (p)
Validierungen
  • (5)
  • (6)
Kat. Nr. ABIN687607
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation FACS, WB, ELISA, IHC
Validierungen
  • (2)
  • (7)
Kat. Nr. ABIN1724812
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Mouse
Applikation WB, IHC, IP, ICC
Validierungen
  • (7)
Kat. Nr. ABIN7440323
Menge 100 μL
Datenblatt Datenblatt

Empfohlene CD33 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6965566
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6965565
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6962469
Menge 96 tests
Datenblatt Datenblatt

Empfohlene CD33 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (4)
Kat. Nr. ABIN7274159
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7275588
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7274160
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CD33 Produkten

Falk, Yazbeck, Guibert, Chamorey, Paquet, Ribeyre, Bence, Zahaf, Leroy, Marquette, Cohen, Mograbi, Mazières, Hofman, Brest, Hofman, Ilié: "Effect of mutant variants of the KRAS gene on PD-L1 expression and on the immune microenvironment and association with clinical outcome in lung adenocarcinoma patients." in: Lung cancer (Amsterdam, Netherlands), Vol. 121, pp. 70-75, (2019) (PubMed).

Son, Diamond, Volpe, Aranow, Mackay, Santiago-Schwarz: "Evidence for C1q-mediated crosslinking of CD33/LAIR-1 inhibitory immunoreceptors and biological control of CD33/LAIR-1 expression." in: Scientific reports, Vol. 7, Issue 1, pp. 270, (2017) (PubMed).

Hagemann, Wickstroem, Wang, Shea, Sponheim, Karlsson, Bjerke, Ryan, Cuthbertson: "In Vitro and In Vivo Efficacy of a Novel CD33-Targeted Thorium-227 Conjugate for the Treatment of Acute Myeloid Leukemia." in: Molecular cancer therapeutics, Vol. 15, Issue 10, pp. 2422-2431, (2016) (PubMed).

Vyas, Schneider, Shatnyeva, Reiners, Tawadros, Kloess, Köhl, Hallek, Hansen, Pogge von Strandmann: "Mono- and dual-targeting triplebodies activate natural killer cells and have anti-tumor activity in vitro and in vivo against chronic lymphocytic leukemia." in: Oncoimmunology, Vol. 5, Issue 9, pp. e1211220, (2016) (PubMed).

Zhou, Ma, Zhou, Jiang, Rao, Zhao, Guo: "miR-17-92 plays an oncogenic role and conveys chemo-resistance to cisplatin in human prostate cancer cells." in: International journal of oncology, Vol. 48, Issue 4, pp. 1737-48, (2016) (PubMed).

Shan, Bu, Zhang, Zhang, Ding, Chang, Dai, Shen, Ma: "LukS-PV, a component of Panton-Valentine leukocidin, exerts potent activity against acute myeloid leukemia in vitro and in vivo." in: The international journal of biochemistry & cell biology, Vol. 61C, pp. 20-28, (2015) (PubMed).

Iwami, Brinkman, Bromberg: "Vascular endothelial growth factor c/vascular endothelial growth factor receptor 3 signaling regulates chemokine gradients and lymphocyte migration from tissues to lymphatics." in: Transplantation, Vol. 99, Issue 4, pp. 668-77, (2015) (PubMed).

Jiang, Li, Shi, Wu, An, Yang, Xu: "Involvement of p38 in signal switching from autophagy to apoptosis via the PERK/eIF2α/ATF4 axis in selenite-treated NB4 cells." in: Cell death & disease, Vol. 5, pp. e1270, (2015) (PubMed).

Ishida, Akita, Mori, Tanida, Toda, Inoue, Nakada: "Negative regulation of Toll-like receptor-4 signaling through the binding of glycosylphosphatidylinositol-anchored glycoprotein, CD14, with the sialic acid-binding lectin, CD33." in: The Journal of biological chemistry, Vol. 289, Issue 36, pp. 25341-50, (2014) (PubMed).

Shi, Jiang, Li, Shan, Li, An, Yang, Xu: "Sodium selenite alters microtubule assembly and induces apoptosis in vitro and in vivo." in: Journal of hematology & oncology, Vol. 6, Issue 1, pp. 7, (2013) (PubMed).

Synonyme und alternative Namen zu CD33

CD33 molecule (CD33), CD33 antigen (Cd33), CD33 molecule (Cd33), gp67, p67, SIGLEC-3, Siglec-3, SIGLEC3

Bezeichner auf Proteinebene für CD33

  • CD33 antigen (gp67)
  • gp67
  • myeloid cell surface antigen CD33
  • sialic acid binding Ig-like lectin 3
  • sialic acid-binding Ig-like lectin 3
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