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CD35 Produkte

(Complement Component Receptor 1 (CD35) (CR1))

Kategorien

This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants, encoding different isoforms, have been characterized. Additional allele specific isoforms, including a secreted form, have been described but have not been fully characterized. [provided by RefSeq, Jul 2008].

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Ausgewählte CD35 Kategorien

CD35 Antikörper

High quality antibodies with extensive validation data.

CD35 ELISA Kits

Reliable ELISA kits for a wide range of species.

Empfohlene CD35 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (7)
Kat. Nr. ABIN7433177
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation IHC, IF
Validierungen
  • (4)
Kat. Nr. ABIN7266477
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Non-Human Primate
Applikation FACS, WB, IHC (p), IP, IHC (fro), ICC
Validierungen
  • (1)
  • (2)
Kat. Nr. ABIN2749062
Menge 0.1 mg
Datenblatt Datenblatt

Empfohlene CD35 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (5)
  • (1)
Kat. Nr. ABIN6955049
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6962520
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN4882188
Menge 96 tests
Datenblatt Datenblatt

Empfohlene CD35 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7393268
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN3008960
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CD35 Produkten

Goetzl, Yaffe, Peltz, Ledreux, Gorgens, Davidson, Granholm, Mustapic, Kapogiannis, Tweedie, Greig: "Traumatic brain injury increases plasma astrocyte-derived exosome levels of neurotoxic complement proteins." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 34, Issue 2, pp. 3359-3366, (2020) (PubMed).

Dave, Sharma, Muir, Haddad, Gumber, Villinger, Nehra, Khan, Wigdahl, Ansari, Byrareddy, Jain: "FDC:TFH Interactions within Cervical Lymph Nodes of SIV-Infected Rhesus Macaques." in: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, Vol. 13, Issue 2, pp. 204-218, (2019) (PubMed).

Sandri, Lidani, Andrade, Meyer, Kremsner, de Messias-Reason, Velavan: "Human complement receptor type 1 (CR1) protein levels and genetic variants in chronic Chagas Disease." in: Scientific reports, Vol. 8, Issue 1, pp. 526, (2018) (PubMed).

Goetzl, Schwartz, Abner, Jicha, Kapogiannis: "High complement levels in astrocyte-derived exosomes of Alzheimer disease." in: Annals of neurology, Vol. 83, Issue 3, pp. 544-552, (2018) (PubMed).

Rovituso, Scheffler, Wunsch, Kleinschnitz, Dörck, Ulzheimer, Bayas, Steinman, Ergün, Kuerten: "CEACAM1 mediates B cell aggregation in central nervous system autoimmunity." in: Scientific reports, Vol. 6, pp. 29847, (2016) (PubMed).

Avanzi, Leoni, Rotola, Alviano, Solimando, Lanzoni, Bonsi, Di Luca, Marchionni, Alvisi, Ripalti: "Susceptibility of human placenta derived mesenchymal stromal/stem cells to human herpesviruses infection." in: PLoS ONE, Vol. 8, Issue 8, pp. e71412, (2013) (PubMed).

Daborg, Andreasson, Pekna, Lautner, Hanse, Minthon, Blennow, Hansson, Zetterberg: "Cerebrospinal fluid levels of complement proteins C3, C4 and CR1 in Alzheimer's disease." in: Journal of neural transmission (Vienna, Austria : 1996), Vol. 119, Issue 7, pp. 789-97, (2012) (PubMed).

Schwartz, Barker, Long, Kaufman, McCracken, Allen: "Natural IgM mediates complement-dependent uptake of Francisella tularensis by human neutrophils via complement receptors 1 and 3 in nonimmune serum." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 6, pp. 3064-77, (2012) (PubMed).

Zhang, Patel, Dey, Ghorani, Rai, Elham, Castleton, Fielding: "Attenuated, oncolytic, but not wild-type measles virus infection has pleiotropic effects on human neutrophil function." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 3, pp. 1002-10, (2012) (PubMed).

Mokuda, Doi, Takasugi: "Simultaneous quantitative analysis of the expression of CD64 and CD35 on neutrophils as markers to differentiate between bacterial and viral infections in patients with rheumatoid arthritis." in: Modern rheumatology, Vol. 22, Issue 5, pp. 750-7, (2012) (PubMed).

Synonyme und alternative Namen zu CD35

complement C3b/C4b receptor 1 (Knops blood group) (CR1), complement receptor 2 (Cr2), complement component (3d/Epstein Barr virus) receptor 2 (CR2), complement receptor type 1 (LOC718120), C3BR, C3DR, C4BR, CD21, CD35, Cr-1, Cr-2, Cr1, CR1, CR1-L, CR2, KN

Bezeichner auf Proteinebene für CD35

  • C3-binding protein
  • C3b/C4b receptor
  • CD35 antigen
  • Knops blood group antigen
  • complement component receptor 1
  • complement receptor type 1
  • complement C3d receptor
  • complement receptor type 2
  • expressed in B lymphocytes
  • LOW QUALITY PROTEIN: complement receptor type 1
  • complement component (3b/4b) receptor 1 (Knops blood group)
  • complement component (3d/Epstein Barr virus) receptor 2
  • complement receptor type 1-like protein
  • cr1 (CD35)
  • complement receptor 1
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