CD70 Produkte
(CD70 Molecule (CD70))
Kategorien
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008].
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Ausgewählte CD70 Kategorien
CD70 Antikörper
High quality antibodies with extensive validation data.
CD70 ELISA Kits
Reliable ELISA kits for a wide range of species.
CD70 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CD70 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (6)
Kat. Nr.
ABIN3022743
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
FACS
Validierungen
- (3)
- (2)
Kat. Nr.
ABIN2749184
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
FACS
Validierungen
- (4)
- (2)
Kat. Nr.
ABIN2749173
Menge
100 tests
Datenblatt
Datenblatt
Empfohlene CD70 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6973491
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6954532
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN1889449
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene CD70 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (4)
Kat. Nr.
ABIN7274227
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (4)
Kat. Nr.
ABIN6961112
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7274243
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CD70 Produkten
: "Inherited CD70 deficiency in humans reveals a critical role for the CD70-CD27 pathway in immunity to Epstein-Barr virus infection." in: The Journal of experimental medicine, Vol. 214, Issue 1, pp. 73-89, (2017) (PubMed).: "Insights into the molecular basis of a bispecific antibody's target selectivity." in: mAbs, Vol. 7, Issue 3, pp. 461-9, (2015) (PubMed).
: "CD70-restricted specific activation of TRAILR1 or TRAILR2 using scFv-targeted TRAIL mutants." in: Cell death & disease, Vol. 5, pp. e1035, (2014) (PubMed).
: "The CD70-CD27 interaction during the stimulation with dendritic cells promotes naive CD4(+) T cells to develop into T cells producing a broad array of immunostimulatory cytokines in humans." in: International immunology, Vol. 21, Issue 8, pp. 891-904, (2009) (PubMed).
: "Proliferation response of leukemic cells to CD70 ligation oscillates with recurrent remission and relapse in a low-grade lymphoma." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 10, pp. 6940-7, (2005) (PubMed).
: "Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 5, pp. 2381-6, (2001) (PubMed).
: "Enhancement of adenovirus vector entry into CD70-positive B-cell Lines by using a bispecific CD70-adenovirus fiber antibody." in: Journal of virology, Vol. 75, Issue 11, pp. 5215-21, (2001) (PubMed).
: "v-Jun sensitizes cells to apoptosis by a mechanism involving mitochondrial cytochrome C release." in: Oncogene, Vol. 19, Issue 51, pp. 5906-18, (2000) (PubMed).
: "Critical contribution of OX40 ligand to T helper cell type 2 differentiation in experimental leishmaniasis." in: The Journal of experimental medicine, Vol. 191, Issue 2, pp. 375-80, (2000) (PubMed).
: "CD27-mediated activation of murine NK cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 164, Issue 4, pp. 1741-5, (2000) (PubMed).
Synonyme und alternative Namen zu CD70
CD70 antigen (Cd70), CD70 molecule (CD70), Cd70 molecule (Cd70), Cd27l, CD27L, CD27LG, Tnfsf7, TNFSF7Bezeichner auf Proteinebene für CD70
- CD27 ligand
- CD27-L
- Ki-24 antigen
- tumor necrosis factor (ligand) superfamily, member 7
- tumor necrosis factor ligand superfamily member 7
- CD70 antigen
- surface antigen CD70
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