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CDC25A Produkte

(Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

Kategorien

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte CDC25A Kategorien

CDC25A Antikörper

High quality antibodies with extensive validation data.

CDC25A ELISA Kits

Reliable ELISA kits for a wide range of species.

CDC25A Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene CDC25A Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (2)
  • (6)
Kat. Nr. ABIN389527
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (6)
Kat. Nr. ABIN3021626
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC, IF, ICC
Validierungen
  • (5)
Kat. Nr. ABIN6255495
Menge 100 μL
Datenblatt Datenblatt

Empfohlene CDC25A ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1380539
Menge 2 x 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1380385
Menge 2 x 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1380738
Menge 2 x 96 tests
Datenblatt Datenblatt

Empfohlene CDC25A Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1348792
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1348790
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN6386706
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CDC25A Produkten

Tang, Cao, Cai, An, Li, Peng, Chen, Luo, Tao, Li: "Epigallocatechin gallate induces chemopreventive effects on rats with diethylnitrosamine‑induced liver cancer via inhibition of cell division cycle 25A." in: Molecular medicine reports, Vol. 22, Issue 5, pp. 3873-3885, (2021) (PubMed).

Chen, Tang, Yang, Li, Huang, Cao: "Silencing CDC25A inhibits the proliferation of liver cancer cells by downregulating IL‑6 in vitro and in vivo." in: International journal of molecular medicine, Vol. 45, Issue 3, pp. 743-752, (2020) (PubMed).

Yuan, Wu, Li, Niu, Tan, Qiu: "Regulation of Signaling Pathways Involved in the Anti-proliferative and Apoptosis-inducing Effects of M22 against Non-small Cell Lung Adenocarcinoma A549 Cells." in: Scientific reports, Vol. 8, Issue 1, pp. 992, (2018) (PubMed).

Wei, Zhang, Ren, Zhang, Liu, Duan, Yu, Li, Peng, Zhou, Sun: "Endosulfan induces cell dysfunction through cycle arrest resulting from DNA damage and DNA damage response signaling pathways." in: The Science of the total environment, Vol. 589, pp. 97-106, (2017) (PubMed).

Blaschke, McKinnon, Nguyen, Holzner, Zehl, Atanasov, Schelch, Krieger, Diaz, Frisch, Feistel, Jäger, Ecker, Dirsch, Grusch, Zupko, Urban, Kopp, Krupitza et al.: "A eudesmane-type sesquiterpene isolated from Pluchea odorata (L.) Cass. combats three hallmarks of cancer cells: Unrestricted proliferation, escape from apoptosis and early metastatic outgrowth in ..." in: Mutation research, Vol. 777, pp. 79-90, (2015) (PubMed).

Neumann, Yang, Köhler, Giaisi, Witzens-Harig, Liu, Krammer, Lin, Li-Weber: "Mangrove dolabrane-type of diterpenes tagalsins suppresses tumor growth via ROS-mediated apoptosis and ATM/ATR-Chk1/Chk2-regulated cell cycle arrest." in: International journal of cancer. Journal international du cancer, (2015) (PubMed).

Wang, Ding, Liu, Li, Wei, Yu, Liu, Ying, Gao, Jiang, Wang: "A novel recurrent CHEK2 Y390C mutation identified in high-risk Chinese breast cancer patients impairs its activity and is associated with increased breast cancer risk." in: Oncogene, (2015) (PubMed).

Liao, Ling, Zhang, Liu, Tao, Han, Chen, Chen, Le: "Cordycepin induces cell cycle arrest and apoptosis by inducing DNA damage and up-regulation of p53 in Leukemia cells." in: Cell cycle (Georgetown, Tex.), Vol. 14, Issue 5, pp. 761-71, (2015) (PubMed).

Zoppoli, Solier, Reinhold, Liu, Connelly, Monks, Shoemaker, Abaan, Davis, Meltzer, Doroshow, Pommier: "CHEK2 genomic and proteomic analyses reveal genetic inactivation or endogenous activation across the 60 cell lines of the US National Cancer Institute." in: Oncogene, Vol. 31, Issue 4, pp. 403-18, (2012) (PubMed).

Unger, Popescu, Giessrigl, Rarova, Herbacek, Seelinger, Diaz, Wallnöfer, Fritzer-Szekeres, Szekeres, Frisch, Doležal, Strnad, De Martin, Grusch, Kopp, Krupitza: "An apolar extract of Critonia morifolia inhibits c-Myc, cyclin D1, Cdc25A, Cdc25B, Cdc25C and Akt and induces apoptosis." in: International journal of oncology, Vol. 40, Issue 6, pp. 2131-9, (2012) (PubMed).

Synonyme und alternative Namen zu CDC25A

cell division cycle 25A (CDC25A), cell division cycle 25A (cdc25a), cell division cycle 25B (cdc25b), cell division cycle 25A (Cdc25a), cell division cycle 25A S homeolog (cdc25a.S), cdc25A, cdc25a2, CDC25A2, D9Ertd393e, sb:cb317

Bezeichner auf Proteinebene für CDC25A

  • cell division cycle 25A
  • cell division cycle 25 homolog A
  • M-phase inducer phosphatase 1
  • Dual specificity phosphatase Cdc25A
  • CDC25A2-CAG isoform
  • dual specificity phosphatase CDC25A
  • dual specificity phosphatase Cdc25A
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