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CDK7 Produkte

(Cyclin-Dependent Kinase 7 (CDK7))

Kategorien

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq, Jul 2008].

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Ausgewählte CDK7 Kategorien

CDK7 Antikörper

High quality antibodies with extensive validation data.

CDK7 ELISA Kits

Reliable ELISA kits for a wide range of species.

CDK7 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene CDK7 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (6)
Kat. Nr. ABIN3022405
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC (p), DB
Validierungen
  • (4)
Kat. Nr. ABIN389541
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, PLA
Validierungen
  • (4)
Kat. Nr. ABIN514290
Menge 100 μg
Datenblatt Datenblatt

Empfohlene CDK7 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6966173
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1380387
Menge 2 x 96 tests
Datenblatt Datenblatt
Reaktivität Pig
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN778532
Menge 96 tests
Datenblatt Datenblatt

Empfohlene CDK7 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1348979
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1348981
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7395140
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CDK7 Produkten

Kokontis, Lin, Jiang, Lin, Fukuchi, Hiipakka, Chung, Chan, Liao, Chang, Chuu: "Androgen suppresses the proliferation of androgen receptor-positive castration-resistant prostate cancer cells via inhibition of Cdk2, CyclinA, and Skp2." in: PLoS ONE, Vol. 9, Issue 10, pp. e109170, (2014) (PubMed).

Devaiah, Singer: "Cross-talk among RNA polymerase II kinases modulates C-terminal domain phosphorylation." in: The Journal of biological chemistry, Vol. 287, Issue 46, pp. 38755-66, (2012) (PubMed).

Ma, Chen, Wright, Pillai, Chellappan, Cress: "CDKN1C negatively regulates RNA polymerase II C-terminal domain phosphorylation in an E2F1-dependent manner." in: The Journal of biological chemistry, Vol. 285, Issue 13, pp. 9813-22, (2010) (PubMed).

White, Dalton: "Cell cycle control of embryonic stem cells." in: Stem cell reviews, Vol. 1, Issue 2, pp. 131-8, (2006) (PubMed).

Syljuåsen, Jensen, Bartek, Lukas: "Adaptation to the ionizing radiation-induced G2 checkpoint occurs in human cells and depends on checkpoint kinase 1 and Polo-like kinase 1 kinases." in: Cancer research, Vol. 66, Issue 21, pp. 10253-7, (2006) (PubMed).

Fisher: "Secrets of a double agent: CDK7 in cell-cycle control and transcription." in: Journal of cell science, Vol. 118, Issue Pt 22, pp. 5171-80, (2005) (PubMed).

Zhou, Deng, Kashanchi, Brady, Shatkin, Kumar: "The Tat/TAR-dependent phosphorylation of RNA polymerase II C-terminal domain stimulates cotranscriptional capping of HIV-1 mRNA." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 22, pp. 12666-71, (2003) (PubMed).

Schneider, Kartarius, Schuster, Montenarh: "The cyclin H/cdk7/Mat1 kinase activity is regulated by CK2 phosphorylation of cyclin H." in: Oncogene, Vol. 21, Issue 33, pp. 5031-7, (2002) (PubMed).

Kino, Tsukamoto, Chrousos: "Transcription factor TFIIH components enhance the GR coactivator activity but not the cell cycle-arresting activity of the human immunodeficiency virus type-1 protein Vpr." in: Biochemical and biophysical research communications, Vol. 298, Issue 1, pp. 17-23, (2002) (PubMed).

Bochar, Pan, Knights, Fisher, Shilatifard, Shiekhattar: "Inhibition of transcription by the trimeric cyclin-dependent kinase 7 complex." in: The Journal of biological chemistry, Vol. 274, Issue 19, pp. 13162-6, (1999) (PubMed).

Synonyme und alternative Namen zu CDK7

cyclin dependent kinase 7 (CDK7), cyclin-dependent kinase 7 (Cdk7), Cyclin-dependent kinase 7 (Cdk7), cyclin-dependent kinase 7 L homeolog (cdk7.L), cyclin-dependent kinase 7 (cdk7), cyclin dependent kinase 7 (Cdk7), AI323415, AI528512, C230069N13, CAK1, cak1, CD 7, cdk-7, CDK7, cdk7, CDKN7, Cdkn7, cdkn7, CG3319, Crk4, dCdk7, DmCDK7, DmCdk7, Dmcdk7, Dmel\\CG3319, DmMO15, DmMo15, HCAK, MO15, Mo15, p39MO15, p39mo15, p40MO15, p40[MO15], STK1, stk1, zgc:85821

Bezeichner auf Proteinebene für CDK7

  • 39 KDa protein kinase
  • CAK
  • CDK-activating kinase 1
  • TFIIH basal transcription factor complex kinase subunit
  • cell division protein kinase 7
  • cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)
  • homolog of Xenopus MO15 Cdk-activating kinase
  • kinase subunit of CAK
  • p39 Mo15
  • protein kinase
  • serine/threonine kinase stk1
  • serine/threonine protein kinase 1
  • serine/threonine protein kinase MO15
  • serine/threonine-protein kinase 1
  • 39 kDa protein kinase
  • CDK-activating kinase
  • CR4 protein kinase
  • CRK4 PK (CDC2-related-kinase-4 protein kinase)
  • P39 Mo15
  • cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase)
  • protein-tyrosine kinase MPK-7
  • 39 protein kinase
  • cyclin-dependent kinase 7 (MO15 homolog Xenopus laevis cdk-activating kinase)
  • CG3319-PA
  • Cdk7-PA
  • Mo15
  • 40 kDa protein kinase
  • CDC2/CDK2,4-activating kinase
  • P40 MO15
  • cyclin-dependent kinase 7 (MO15, cdk-activating kinase)
  • cell division protein kinase 7-like protein
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