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CDKN1C Produkte

(Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010].

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Ausgewählte CDKN1C Kategorien

CDKN1C Antikörper

High quality antibodies with extensive validation data.

CDKN1C ELISA Kits

Reliable ELISA kits for a wide range of species.

CDKN1C Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene CDKN1C Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, FACS, IHC, ICC
Validierungen
  • (8)
Kat. Nr. ABIN7193626
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, FACS, IHC
Validierungen
  • (6)
Kat. Nr. ABIN7193625
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation IHC (f)
Validierungen
  • (3)
Kat. Nr. ABIN7504181
Menge 100 μg
Datenblatt Datenblatt

Empfohlene CDKN1C ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1380426
Menge 2 x 96 tests
Datenblatt Datenblatt

Empfohlene CDKN1C Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7122539
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1349015
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3091606
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CDKN1C Produkten

Zhang, Li, Dong, Wu: "Long non-coding RNA NEAT1 regulates E2F3 expression by competitively binding to miR-377 in non-small cell lung cancer." in: Oncology letters, Vol. 14, Issue 4, pp. 4983-4988, (2018) (PubMed).

Mochizuki, Tamai, Imai, Sugawara, Ogama, Nakamura, Matsuura, Yamaguchi, Satoh, Sato, Motohashi, Sugamura, Tanaka: "CD271 regulates the proliferation and motility of hypopharyngeal cancer cells." in: Scientific reports, Vol. 6, pp. 30707, (2016) (PubMed).

Ma, Chen, Wright, Pillai, Chellappan, Cress: "CDKN1C negatively regulates RNA polymerase II C-terminal domain phosphorylation in an E2F1-dependent manner." in: The Journal of biological chemistry, Vol. 285, Issue 13, pp. 9813-22, (2010) (PubMed).

Graña, Reddy: "Cell cycle control in mammalian cells: role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs)." in: Oncogene, Vol. 11, Issue 2, pp. 211-9, (1995) (PubMed).

Lee, Reynisdóttir, Massagué: "Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution." in: Genes & development, Vol. 9, Issue 6, pp. 639-49, (1995) (PubMed).

Matsuoka, Edwards, Bai, Parker, Zhang, Baldini, Harper, Elledge: "p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene." in: Genes & development, Vol. 9, Issue 6, pp. 650-62, (1995) (PubMed).

Synonyme und alternative Namen zu CDKN1C

cyclin dependent kinase inhibitor 1C (CDKN1C), cyclin-dependent kinase inhibitor 1Ca (cdkn1ca), cyclin-dependent kinase inhibitor 1C (P57) (Cdkn1c), cyclin-dependent kinase inhibitor 1C (Cdkn1c), AL024410, BWCR, BWS, cb961, CDKI, KIP2, Kip2, p27Xic1-a, p57, p57(kip2), p57Kip2, p57KIP2, WBS, zgc:86618

Bezeichner auf Proteinebene für CDKN1C

  • cyclin-dependent kinase inhibitor 1C
  • cyclin-dependent kinase inhibitor p57
  • cyclin-dependent kinase inhibitor 1C (p57, Kip2)
  • p57kip2
  • cyclin-dependent kinase inhibitor 1C, p57
  • p57KIP2 A3sh
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