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CES2 Produkte

(Carboxylesterase 2 (CES2))

Kategorien

This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2010].

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Ausgewählte CES2 Kategorien

CES2 Antikörper

High quality antibodies with extensive validation data.

CES2 ELISA Kits

Reliable ELISA kits for a wide range of species.

CES2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene CES2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, FACS, IHC (p)
Validierungen
  • (2)
  • (6)
Kat. Nr. ABIN654618
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p)
Validierungen
  • (2)
  • (5)
Kat. Nr. ABIN563817
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Dog, Guinea Pig, Human, Mouse, Rat
Applikation WB, IHC
Validierungen
  • (1)
  • (5)
Kat. Nr. ABIN2775271
Menge 100 μL
Datenblatt Datenblatt

Empfohlene CES2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6999583
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6954570
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN4882308
Menge 96 tests
Datenblatt Datenblatt

Empfohlene CES2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7122138
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1349174
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1349176
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CES2 Produkten

Lacombe, Jaquinod, Belmudes, Couté, Ramus, Combes, Burger, Mintz, Barthelon, Leroy, Poujois, Lachaux, Woimant, Brun: "Comprehensive and comparative exploration of the Atp7b-/- mouse plasma proteome." in: Metallomics : integrated biometal science, Vol. 12, Issue 2, pp. 249-258, (2021) (PubMed).

Kailass, Sadovski, Capello, Kang, Fleming, Hanash, Beharry: "Measuring human carboxylesterase 2 activity in pancreatic cancer patient-derived xenografts using a ratiometric fluorescent chemosensor." in: Chemical science, Vol. 10, Issue 36, pp. 8428-8437, (2019) (PubMed).

Hines, Simpson, McCarver: "Age-Dependent Human Hepatic Carboxylesterase 1 (CES1) and Carboxylesterase 2 (CES2) Postnatal Ontogeny." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 44, Issue 7, pp. 959-66, (2016) (PubMed).

Shang, Liu, Chen, Ning, Xiong, Liu, Mao, Hu, Yang: "Fluoxetine reduces CES1, CES2, and CYP3A4 expression through decreasing PXR and increasing DEC1 in HepG2 cells." in: Xenobiotica; the fate of foreign compounds in biological systems, pp. 1-13, (2015) (PubMed).

Chen, Wang, Ning, Hu, Liu, Xiong, Wu, Liu, Hu, Yang: "Decreased carboxylesterases expression and hydrolytic activity in type 2 diabetic mice through Akt/mTOR/HIF-1?/Stra13 pathway." in: Xenobiotica; the fate of foreign compounds in biological systems, pp. 1-12, (2015) (PubMed).

Pratt, Durland-Busbice, Shepard, Heinz-Taheny, Iversen, Dantzig: "Human carboxylesterase-2 hydrolyzes the prodrug of gemcitabine (LY2334737) and confers prodrug sensitivity to cancer cells." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 19, Issue 5, pp. 1159-68, (2013) (PubMed).

Uchida, Otake, Tanaka, Hashimoto, Saigusa, Matsushita, Koike, Inoue, Ueeda, Okugawa, Inoue, Mohri, Kusunoki: "Clinical implications of CES2 RNA expression in neuroblastoma." in: Journal of pediatric surgery, Vol. 48, Issue 3, pp. 502-9, (2013) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Wong, Cheng, Xie, Zhou, Zhu, Constantinides, Rigas: "Carboxylesterases 1 and 2 hydrolyze phospho-nonsteroidal anti-inflammatory drugs: relevance to their pharmacological activity." in: The Journal of pharmacology and experimental therapeutics, Vol. 340, Issue 2, pp. 422-32, (2012) (PubMed).

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Synonyme und alternative Namen zu CES2

carboxylesterase 2 (CES2), carboxylesterase 2 (Ces2), liver carboxylesterase 2 (LOC100343300), cocaine esterase (LOC100734360), carboxylesterase 2 (intestine, liver) (ces2), CE-2, ce-2, Ces2, CES2A1, ces2a1, iCE, im:6908784, PCE-2, pce-2, si:dkey-38l12.2, zgc:153863

Bezeichner auf Proteinebene für CES2

  • carboxylesterase 2 (intestine, liver)
  • cocaine esterase
  • hCE-2
  • intestinal carboxylesterase; liver carboxylesterase-2
  • methylumbelliferyl-acetate deacetylase 2
  • liver carboxylesterase 2
  • carboxylesterase 2
  • carboxylesterase 2-like
  • carboxylesterase 5A
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