CHD8 Produkte
(Chromodomain Helicase DNA Binding Protein 8 (CHD8))
Kategorien
This gene encodes a DNA helicase that functions as a transcription repressor by remodeling chromatin structure. It binds beta-catenin and negatively regulates Wnt signaling pathway, which plays a pivotal role in vertebrate early development and morphogenesis. Mice lacking this gene exhibit early embryonic death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010].
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Ausgewählte CHD8 Kategorien
CHD8 Antikörper
High quality antibodies with extensive validation data.
Empfohlene CHD8 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC, ELISA
Validierungen
- (3)
Kat. Nr.
ABIN6260798
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN566153
Menge
50 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (1)
Kat. Nr.
ABIN1774862
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene CHD8 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1349296
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7422676
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CHD8 Produkten
: "Common CHD8 Genomic Targets Contrast With Model-Specific Transcriptional Impacts of CHD8 Haploinsufficiency." in: Frontiers in molecular neuroscience, Vol. 11, pp. 481, (2018) (PubMed).: "Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits." in: Cell reports, Vol. 19, Issue 2, pp. 335-350, (2017) (PubMed).
: "BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors." in: Journal of proteomics, Vol. 118, pp. 95-111, (2015) (PubMed).
: "CHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 42, pp. E4468-77, (2014) (PubMed).
: "Frequent disruption of chromodomain helicase DNA-binding protein 8 (CHD8) and functionally associated chromatin regulators in prostate cancer." in: Neoplasia (New York, N.Y.), Vol. 16, Issue 12, pp. 1018-27, (2014) (PubMed).
: "Regulation of serum response factor activity and smooth muscle cell apoptosis by chromodomain helicase DNA-binding protein 8." in: American journal of physiology. Cell physiology, Vol. 299, Issue 5, pp. C1058-67, (2010) (PubMed).
Synonyme und alternative Namen zu CHD8
chromodomain helicase DNA binding protein 8 (CHD8), chromodomain helicase DNA binding protein 8 (chd8), chromodomain helicase DNA binding protein 8 (Chd8), 5830451P18Rik, AU015341, AUTS18, CHD-8, CHD8, Chd8, Duplin, fi45h08, HELSNF1, mKIAA1564, si:ch211-10e2.6, wu:fi45h08Bezeichner auf Proteinebene für CHD8
- chromodomain helicase DNA binding protein 8
- chromodomain-helicase-DNA-binding protein 8
- ATP-dependent helicase CHD8
- chromodomain-helicase-DNA-binding protein 8-like
- axis duplication inhibitor
- duplin
- helicase with SNF2 domain 1
- CHD-8
- beta-catenin binding protein
- chromodomain helicase DNA binding protein family
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