CHEK1 Proteine
(Checkpoint Kinase 1 (CHEK1))
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011].
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CHEK1
Spezies: Human
Wirt: Baculovirus infected Insect Cells
Recombinant
> 90 % as determined by reducing SDS-PAGE.
Active
1 image
CHEK1
Spezies: Maus
Wirt: Baculovirus infected Insect Cells
Recombinant
> 90 % as determined by SDS-PAGE
1 image
CHEK1
Spezies: Human
Wirt: Insektenzellen
Recombinant
70 % - 90 %
Func
Active
CHEK1
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
custom-made
CHEK1
Spezies: Maus
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
custom-made
CHEK1
Spezies: Human
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
CHEK1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
CHEK1
Spezies: Schizosaccharomyces pombe
Wirt: Hefe
Recombinant
> 90 %
ELISA
Aktuelle Publikationen für unsere CHEK1 Proteine
: "Caspase 3/caspase-activated DNase promote cell differentiation by inducing DNA strand breaks." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 9, pp. 4230-5, (2010) (PubMed).Aliase für CHEK1 Proteine
checkpoint kinase 1 (CHEK1) Proteineserine/threonine-protein kinase chk1 (ANI_1_2436074) Proteine
serine/threonine-protein kinase chk1 (AOR_1_768154) Proteine
serine/threonine-protein kinase Chk1 (PTRG_04183) Proteine
CAMK/CAMKL/CHK1 protein kinase Chk1 (SJAG_01680) Proteine
serine/threonine-protein kinase chk1 (PAAG_04978) Proteine
serine/threonine-protein kinase chk1 (MCYG_03290) Proteine
serine/threonine-protein kinase chk1 (VDBG_03742) Proteine
checkpoint kinase 1 S homeolog (chek1.S) Proteine
checkpoint kinase 1 (Chek1) Proteine
checkpoint kinase 1 (chek1) Proteine
An08g10320 Proteine
AO090003000441 Proteine
C85740 Proteine
CHEK1 Proteine
CHK1 Proteine
chk1 Proteine
Chk1 Proteine
id:ibd2720 Proteine
rad27 Proteine
zgc:56093 Proteine
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