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CHMP4B Produkte

(Charged Multivesicular Body Protein 4B (CHMP4B))

Kategorien

This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies. Mutations in this gene result in autosomal dominant posterior polar cataracts.[provided by RefSeq, Oct 2009].

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Ausgewählte CHMP4B Kategorien

CHMP4B Antikörper

High quality antibodies with extensive validation data.

CHMP4B Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene CHMP4B Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Rat
Applikation ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Validierungen
  • (4)
Kat. Nr. ABIN872575
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, FACS, IHC (p)
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN653481
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (4)
Kat. Nr. ABIN6138549
Menge 100 μL
Datenblatt Datenblatt

Empfohlene CHMP4B ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6228058
Menge 96 tests
Datenblatt Datenblatt

Empfohlene CHMP4B Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN2713984
Menge 20 μg
Datenblatt Datenblatt
Reaktivität Zebrafish (Danio rerio)
Source Yeast
Validierungen
Kat. Nr. ABIN1677542
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Chicken
Source Yeast
Validierungen
Kat. Nr. ABIN1635181
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CHMP4B Produkten

Hu, Jiang, Chen, Wei, Zhang, Zhao, Ni, Lu, Wan: "High CHMP4B expression is associated with accelerated cell proliferation and resistance to doxorubicin in hepatocellular carcinoma." in: Tumour biology, Vol. 36, Issue 4, pp. 2569-81, (2015) (PubMed).

Bodon, Chassefeyre, Pernet-Gallay, Martinelli, Effantin, Hulsik, Belly, Goldberg, Chatellard-Causse, Blot, Schoehn, Weissenhorn, Sadoul: "Charged multivesicular body protein 2B (CHMP2B) of the endosomal sorting complex required for transport-III (ESCRT-III) polymerizes into helical structures deforming the plasma membrane." in: The Journal of biological chemistry, Vol. 286, Issue 46, pp. 40276-86, (2011) (PubMed).

Synonyme und alternative Namen zu CHMP4B

charged multivesicular body protein 4B (CHMP4B), charged multivesicular body protein 4B (Chmp4b), charged multivesicular body protein 4Ba (chmp4ba), charged multivesicular body protein 4B L homeolog (chmp4b.L), charged multivesicular body protein 4Bb (chmp4bb), 2010012F05Rik, C20orf178, c20orf178, C76846, CHMP4A, CHMP4b, chmp4b, chmp4b.S, CHMP4c, CTPP3, CTRCT31, dJ553F4.4, RGD1309846, RGD1565889, Shax1, SNF7, SNF7-2, Snf7-2, Vps32-2, VPS32B, wu:fc96b02, zgc:55566

Bezeichner auf Proteinebene für CHMP4B

  • SNF7 homolog associated with Alix 1
  • Snf7 homologue associated with Alix 1
  • charged multivesicular body protein 4b
  • chromatin modifying protein 4B
  • chromatin-modifying protein 4b
  • hSnf7-2
  • hVps32-2
  • vacuolar protein sorting-associated protein 32-2
  • vacuolar protein-sorting-associated protein 32-2
  • CHMP4b
  • Chromatin-modifying protein 4b
  • charged multivesicular body protein 4B S homeolog
  • CHMP4c
  • Chromatin-modifying protein 4c
  • charged multivesicular body protein 4B
  • charged multivesicular body protein 4c
  • chromatin-modifying protein 4c
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