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CHRFAM7A Produkte

(CHRNA7 (Cholinergic Receptor, Nicotinic, alpha 7, Exons 5-10) and FAM7A (Family with Sequence Similarity 7A, Exons A-E) Fusion (CHRFAM7A))

Kategorien

The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. [provided by RefSeq, Jul 2008].

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Ausgewählte CHRFAM7A Kategorien

CHRFAM7A Antikörper

High quality antibodies with extensive validation data.

Empfohlene CHRFAM7A Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC
Validierungen
  • (3)
Kat. Nr. ABIN7147675
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Applikation WB
Validierungen
  • (1)
  • (2)
Kat. Nr. ABIN2776280
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Rat
Applikation WB, ELISA, IHC
Validierungen
  • (3)
Kat. Nr. ABIN6098837
Menge 100 μL
Datenblatt Datenblatt

Empfohlene CHRFAM7A ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6229401
Menge 96 tests
Datenblatt Datenblatt

Empfohlene CHRFAM7A Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3100532
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CHRFAM7A Produkten

Martin, Leonard, Hall, Tregellas, Freedman, Olincy: "Sensory gating and alpha-7 nicotinic receptor gene allelic variants in schizoaffective disorder, bipolar type." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 144B, Issue 5, pp. 611-4, (2007) (PubMed).

Trombino, Cesario, Margaritora, Granone, Motta, Falugi, Russo: "Alpha7-nicotinic acetylcholine receptors affect growth regulation of human mesothelioma cells: role of mitogen-activated protein kinase pathway." in: Cancer research, Vol. 64, Issue 1, pp. 135-45, (2004) (PubMed).

Bevilacqua, Nelson: "Endothelial-leukocyte adhesion molecules in inflammation and metastasis." in: Thrombosis and haemostasis, Vol. 70, Issue 1, pp. 152-4, (1993) (PubMed).

García Prats, López Carreira, Martínez-González, Ballestín, Gil, De Prada: "Granular cell basal cell carcinoma. Light microscopy, immunohistochemical and ultrastructural study." in: Virchows Archiv. A, Pathological anatomy and histopathology, Vol. 422, Issue 2, pp. 173-7, (1993) (PubMed).

Groves, Allen, Ross, Ahsan, Barker, MacDonald: "Expression of selectin ligands by cutaneous squamous cell carcinoma." in: The American journal of pathology, Vol. 143, Issue 4, pp. 1220-5, (1993) (PubMed).

Ma, Zarbo, Frierson, Lee: "Comparative immunohistochemical study of primary and metastatic carcinomas of the liver." in: American journal of clinical pathology, Vol. 99, Issue 5, pp. 551-7, (1993) (PubMed).

Narita, Funahashi, Satoh, Watanabe, Sakamoto, Takagi: "Association of expression of blood group-related carbohydrate antigens with prognosis in breast cancer." in: Cancer, Vol. 71, Issue 10, pp. 3044-53, (1993) (PubMed).

Paties, Taccagni, Papotti, Valente, Zangrandi, Aloi: "Apocrine carcinoma of the skin. A clinicopathologic, immunocytochemical, and ultrastructural study." in: Cancer, Vol. 71, Issue 2, pp. 375-81, (1993) (PubMed).

Torii, Nakayama, Harada, Nakao, Nonami, Sakamoto, Watanabe, Ito, Takagi: "Expression of the CD15 antigen in hepatocellular carcinoma." in: Cancer, Vol. 71, Issue 12, pp. 3864-7, (1993) (PubMed).

McCormick, Zetter: "Adhesive interactions in angiogenesis and metastasis." in: Pharmacology & therapeutics, Vol. 53, Issue 2, pp. 239-60, (1992) (PubMed).

Synonyme und alternative Namen zu CHRFAM7A

CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion (CHRFAM7A), CHRNA7, CHRNA7-DR1, D-10

Bezeichner auf Proteinebene für CHRFAM7A

  • CHRNA7 (cholinergic receptor, nicotinic, alpha polypeptide 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
  • CHRNA7-FAM7A fusion protein
  • alpha 7 neuronal nicotinic acetylcholine receptor-FAM7A hybrid
  • alpha-7 nicotinic cholinergic receptor subunit
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