Claspin Produkte
(Claspin (CLSPN))
Kategorien
The product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage. The protein is also required for efficient DNA replication during a normal S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].
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Ausgewählte Claspin Kategorien
Claspin Antikörper
High quality antibodies with extensive validation data.
Empfohlene Claspin Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN6260859
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (1)
Kat. Nr.
ABIN7266402
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
Kat. Nr.
ABIN6388311
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Claspin ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Validierungen
Kat. Nr.
ABIN1126688
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1126689
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Claspin Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3091815
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3136084
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Claspin Produkten
: "Kinase-independent function of checkpoint kinase 1 (Chk1) in the replication of damaged DNA." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 19, pp. 7344-9, (2012) (PubMed).: "Claspin as a biomarker of human papillomavirus-related high grade lesions of uterine cervix." in: Journal of translational medicine, Vol. 10, pp. 132, (2012) (PubMed).
: "USP1 deubiquitinase maintains phosphorylated CHK1 by limiting its DDB1-dependent degradation." in: Human molecular genetics, Vol. 20, Issue 11, pp. 2171-81, (2011) (PubMed).
: "ATR/Chk1 pathway is essential for resumption of DNA synthesis and cell survival in UV-irradiated XP variant cells." in: Human molecular genetics, Vol. 19, Issue 9, pp. 1690-701, (2010) (PubMed).
: "NK cells recognize and kill human glioblastoma cells with stem cell-like properties." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 6, pp. 3530-9, (2009) (PubMed).
: "Cdh1 regulates cell cycle through modulating the claspin/Chk1 and the Rb/E2F1 pathways." in: Molecular biology of the cell, Vol. 20, Issue 14, pp. 3305-16, (2009) (PubMed).
: "Loss of CHK1 function impedes DNA damage-induced FANCD2 monoubiquitination but normalizes the abnormal G2 arrest in Fanconi anemia." in: Human molecular genetics, Vol. 17, Issue 5, pp. 679-89, (2008) (PubMed).
: "Chk1 and Claspin potentiate PCNA ubiquitination." in: Genes & development, Vol. 22, Issue 9, pp. 1147-52, (2008) (PubMed).
: "Phosphatase type 2A-dependent and -independent pathways for ATR phosphorylation of Chk1." in: The Journal of biological chemistry, Vol. 282, Issue 10, pp. 7287-98, (2007) (PubMed).
: "Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint." in: The Journal of biological chemistry, Vol. 282, Issue 4, pp. 2729-40, (2007) (PubMed).
Synonyme und alternative Namen zu Claspin
claspin (Clspn), claspin (CLSPN), claspin (clspn), claspin S homeolog (clspn.S), B130025E01, C85083, CLSPN, E130314M08Rik, xClaspinBezeichner auf Proteinebene für Claspin
- claspin homolog (Xenopus laevis)
- claspin
- claspin homolog
- hClaspin
- xClaspin
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