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CLEC14A Produkte

(C-Type Lectin Domain Family 14, Member A (CLEC14A))

Kategorien

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This family member plays a role in cell-cell adhesion and angiogenesis. It functions in filopodia formation, cell migration and tube formation. Due to its presence at higher levels in tumor endothelium than in normal tissue endothelium, it is considered to be a candidate for tumor vascular targeting. [provided by RefSeq, Jan 2012].

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Ausgewählte CLEC14A Kategorien

CLEC14A Antikörper

High quality antibodies with extensive validation data.

CLEC14A ELISA Kits

Reliable ELISA kits for a wide range of species.

CLEC14A Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene CLEC14A Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IF (p), IHC (p)
Validierungen
  • (3)
  • (1)
Kat. Nr. ABIN1385496
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (3)
Kat. Nr. ABIN531111
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC
Validierungen
  • (1)
Kat. Nr. ABIN7146053
Menge 100 μg
Datenblatt Datenblatt

Empfohlene CLEC14A ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6730716
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN4882375
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6386088
Menge 96 tests
Datenblatt Datenblatt

Empfohlene CLEC14A Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7274362
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7274351
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7122062
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CLEC14A Produkten

Kim, Park, Jang, Kim, Na, Lee, Kim, Heo, Yoo, Kim, Lee, Kim, Kim, Kim, Cha, Lee, Lee: "Inhibition of VEGF-dependent angiogenesis and tumor angiogenesis by an optimized antibody targeting CLEC14a." in: Molecular oncology, Vol. 12, Issue 3, pp. 356-372, (2019) (PubMed).

Botting, Bertram, Baharlou, Sandgren, Fletcher, Rhodes, Rana, Plasto, Wang, Lim, Barnouti, Kohout, Papadopoulos, Merten, Olbourne, Cunningham, Haniffa, Harman: "Phenotypic and functional consequences of different isolation protocols on skin mononuclear phagocytes." in: Journal of leukocyte biology, Vol. 101, Issue 6, pp. 1393-1403, (2017) (PubMed).

Jang, Kim, Kim, Lee, Kim, Heo, Lee: "CLEC14a-HSP70-1A interaction regulates HSP70-1A-induced angiogenesis." in: Scientific reports, Vol. 7, Issue 1, pp. 10666, (2017) (PubMed).

Noy, Swain, Khan, Lodhia, Bicknell: "Sprouting angiogenesis is regulated by shedding of the C-type lectin family 14, member A (CLEC14A) ectodomain, catalyzed by rhomboid-like 2 protein (RHBDL2)." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 30, Issue 6, pp. 2311-23, (2016) (PubMed).

Noy, Lodhia, Khan, Zhuang, Ward, Verissimo, Bacon, Bicknell: "Blocking CLEC14A-MMRN2 binding inhibits sprouting angiogenesis and tumour growth." in: Oncogene, (2015) (PubMed).

Ki, Jeoung, Choi, Rho, Kwon, Shim, Chung, Hong, Song, Lee: "Human antibodies targeting the C-type lectin-like domain of the tumor endothelial cell marker clec14a regulate angiogenic properties in vitro." in: Oncogene, Vol. 32, Issue 48, pp. 5449-57, (2013) (PubMed).

Mura, Swain, Zhuang, Vorschmitt, Reynolds, Durant, Beesley, Herbert, Sheldon, Andre, Sanderson, Glen, Luu, McGettrick, Antczak, Falciani, Nash, Nagy, Bicknell: "Identification and angiogenic role of the novel tumor endothelial marker CLEC14A." in: Oncogene, Vol. 31, Issue 3, pp. 293-305, (2012) (PubMed).

Galvagni, Nardi, Spiga, Trezza, Tarticchio, Pellicani, Andreuzzi, Caldi, Toti, Tosi, Santucci, Iozzo, Mongiat, Orlandini: "Dissecting the CD93-Multimerin 2 interaction involved in cell adhesion and migration of the activated endothelium." in: Matrix biology : journal of the International Society for Matrix Biology, Vol. 64, pp. 112-127 (PubMed).

Synonyme und alternative Namen zu CLEC14A

C-type lectin domain containing 14A (CLEC14A), C-type lectin domain family 14, member a (Clec14a), 1200003C23Rik, AI642649, C14orf27, CEG1, EGFR-5

Bezeichner auf Proteinebene für CLEC14A

  • C-type lectin domain family 14 member A
  • ClECT and EGF-like domain containing protein
  • epidermal growth factor receptor 5
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