CNTNAP2 Produkte
(Contactin Associated Protein-Like 2 (CNTNAP2))
Kategorien
This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It is directly bound and regulated by forkhead box protein P2 (FOXP2), a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and mental retardation.[provided by RefSeq, Mar 2010].
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Ausgewählte CNTNAP2 Kategorien
CNTNAP2 Antikörper
High quality antibodies with extensive validation data.
CNTNAP2 ELISA Kits
Reliable ELISA kits for a wide range of species.
CNTNAP2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CNTNAP2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (2)
Kat. Nr.
ABIN652646
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IP
Validierungen
- (2)
Kat. Nr.
ABIN949170
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Rat
Applikation
WB, ELISA, FACS
Validierungen
- (1)
Kat. Nr.
ABIN1386423
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene CNTNAP2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966064
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6730471
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN4882106
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene CNTNAP2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN7320203
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7413064
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
Kat. Nr.
ABIN7538789
Menge
2 x 100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CNTNAP2 Produkten
: "Synaptic abnormalities and cytoplasmic glutamate receptor aggregates in contactin associated protein-like 2/Caspr2 knockout neurons." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 19, pp. 6176-81, (2015) (PubMed).: "Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes." in: Biochimica et biophysica acta, Vol. 1854, Issue 7, pp. 827-33, (2015) (PubMed).
: "Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture." in: Nature, Vol. 500, Issue 7461, pp. 217-21, (2013) (PubMed).
: "Morvan syndrome: clinical and serological observations in 29 cases." in: Annals of neurology, Vol. 72, Issue 2, pp. 241-55, (2012) (PubMed).
: "Clustering and activity tuning of Kv1 channels in myelinated hippocampal axons." in: The Journal of biological chemistry, Vol. 286, Issue 29, pp. 25835-47, (2011) (PubMed).
: "Molecular microdomains in a sensory terminal, the vestibular calyx ending." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 27, pp. 10101-14, (2011) (PubMed).
: "Genome-wide association study with DNA pooling identifies variants at CNTNAP2 associated with pseudoexfoliation syndrome." in: European journal of human genetics : EJHG, Vol. 19, Issue 2, pp. 186-93, (2011) (PubMed).
: "Organization of myelinated axons by Caspr and Caspr2 requires the cytoskeletal adapter protein 4.1B." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 7, pp. 2480-9, (2010) (PubMed).
: "Human myelin proteome and comparative analysis with mouse myelin." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 34, pp. 14605-10, (2009) (PubMed).
Synonyme und alternative Namen zu CNTNAP2
contactin associated protein like 2 (CNTNAP2), contactin associated protein-like 2 (Cntnap2), contactin associated protein-like 2 (CNTNAP2), contactin associated protein like 2b (cntnap2b), contactin associated protein like 2 (cntnap2), contactin associated protein like 2 (Cntnap2), 5430425M22Rik, AUTS15, CASPR, CASPR2, Caspr2, CDFE, MGC145769, MGC147944, MGC147981, mKIAA0868, NRXN4, PTHSL1Bezeichner auf Proteinebene für CNTNAP2
- cell recognition molecule Caspr2
- contactin-associated protein-like 2
- homolog of Drosophila neurexin IV
- contactin associated protein-like 2
- novel protein similar to H.sapiens contactin associated protein
- contactin associated protein 2
- contactin-associated protein-like 2-like
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