COCH Produkte
(Cochlin (COCH))
Kategorien
The protein encoded by this gene is highly conserved in human, mouse, and chicken, showing 94% and 79% amino acid identity of human to mouse and chicken sequences, respectively. Hybridization to this gene was detected in spindle-shaped cells located along nerve fibers between the auditory ganglion and sensory epithelium. These cells accompany neurites at the habenula perforata, the opening through which neurites extend to innervate hair cells. This and the pattern of expression of this gene in chicken inner ear paralleled the histologic findings of acidophilic deposits, consistent with mucopolysaccharide ground substance, in temporal bones from DFNA9 (autosomal dominant nonsyndromic sensorineural deafness 9) patients. Mutations that cause DFNA9 have been reported in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. Additional splice variants encoding distinct isoforms have been described but their biological validities have not been demonstrated. [provided by RefSeq, Oct 2008].
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Ausgewählte COCH Kategorien
COCH Antikörper
High quality antibodies with extensive validation data.
COCH ELISA Kits
Reliable ELISA kits for a wide range of species.
COCH Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene COCH Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, FACS, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN656833
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7148039
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (2)
Kat. Nr.
ABIN655279
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene COCH ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6954851
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN4882435
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6386083
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene COCH Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1349913
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
Kat. Nr.
ABIN6253496
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
Kat. Nr.
ABIN6253494
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren COCH Produkten
: "Cleaved Cochlin Sequesters Pseudomonas aeruginosa and Activates Innate Immunity in the Inner Ear." in: Cell host & microbe, Vol. 25, Issue 4, pp. 513-525.e6, (2019) (PubMed).: "Activation of human endothelial cells via S-endo-1 antigen (CD146) stimulates the tyrosine phosphorylation of focal adhesion kinase p125(FAK)." in: The Journal of biological chemistry, Vol. 273, Issue 41, pp. 26852-6, (1998) (PubMed).
: "Loss of AP-2 results in up-regulation of MCAM/MUC18 and an increase in tumor growth and metastasis of human melanoma cells." in: The Journal of biological chemistry, Vol. 273, Issue 26, pp. 16501-8, (1998) (PubMed).
: "Expression of MCAM/MUC18 by human melanoma cells leads to increased tumor growth and metastasis." in: Cancer research, Vol. 57, Issue 11, pp. 2295-303, (1997) (PubMed).
: "MUC18, a marker of tumor progression in human melanoma, shows sequence similarity to the neural cell adhesion molecules of the immunoglobulin superfamily." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 24, pp. 9891-5, (1990) (PubMed).
Synonyme und alternative Namen zu COCH
cochlin (Coch), cochlin (COCH), AW122937, Coch-5B2, COCH-5B2, COCH5B2, D12H14S564E, DFNA9Bezeichner auf Proteinebene für COCH
- coagulation factor C homolog (Limulus polyphemus)
- coagulation factor C homolog, cochlin (Limulus polyphemus)
- cochlin
- Coch-5B2
Haben Sie etwas anderes gesucht?
- COBRA1
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- COASY
- Coagulation Factor X
- Coagulation Factor VIII-Associated 1
- Coagulation Factor VIIa
- Coagulation Factor V
- Coagulation Factor IX
- Coagulation Factor II (thrombin) Receptor-Like 2
- COA6
- COA5
- COA4
- COA2
- CO5A2
- Co-Chaperonin GroES
- CNTROB
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