COL4a3 Produkte
(Collagen, Type IV, alpha 3 (COL4A3))
Kategorien
Type IV collagen, the major structural component of basement membranes, is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 through alpha 6, each of which can form a triple helix structure with 2 other subunits to form type IV collagen. This gene encodes alpha 3. In the Goodpasture syndrome, autoantibodies bind to the collagen molecules in the basement membranes of alveoli and glomeruli. The epitopes that elicit these autoantibodies are localized largely to the non-collagenous C-terminal domain of the protein. A specific kinase phosphorylates amino acids in this same C-terminal region and the expression of this kinase is upregulated during pathogenesis. This gene is also linked to an autosomal recessive form of Alport syndrome. The mutations contributing to this syndrome are also located within the exons that encode this C-terminal region. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. [provided by RefSeq, Jun 2010].
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Ausgewählte COL4a3 Kategorien
COL4a3 Antikörper
High quality antibodies with extensive validation data.
COL4a3 ELISA Kits
Reliable ELISA kits for a wide range of species.
COL4a3 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene COL4a3 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (4)
Kat. Nr.
ABIN7434707
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse, Rat
Applikation
ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
- (2)
- (2)
Kat. Nr.
ABIN678128
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (2)
Kat. Nr.
ABIN7266460
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene COL4a3 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6954946
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5653131
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene COL4a3 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN7321080
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7395947
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN5709311
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren COL4a3 Produkten
: "The impairment of intramural periarterial drainage in brain after subarachnoid hemorrhage." in: Acta neuropathologica communications, Vol. 10, Issue 1, pp. 187, (2022) (PubMed).: "T3 peptide, a fragment of tumstatin, stimulates proliferation and migration of cardiac fibroblasts through activation of Akt signaling pathway." in: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 390, Issue 11, pp. 1135-1144, (2017) (PubMed).
: "Everolimus Stabilizes Podocyte Microtubules via Enhancing TUBB2B and DCDC2 Expression." in: PLoS ONE, Vol. 10, Issue 9, pp. e0137043, (2015) (PubMed).
: "The expression and activity of cathepsins D, H and K in asthmatic airways." in: PLoS ONE, Vol. 8, Issue 3, pp. e57245, (2013) (PubMed).
: "A new anti-tumor strategy based on in vivo tumstatin overexpression after plasmid electrotransfer in muscle." in: Biochemical and biophysical research communications, Vol. 432, Issue 4, pp. 549-52, (2013) (PubMed).
: "The role of TG2 in ECV304-related vasculogenic mimicry." in: Amino acids, Vol. 44, Issue 1, pp. 89-101, (2013) (PubMed).
: "Cellular and transcriptomic analysis of human mesenchymal stem cell response to plasma-activated hydroxyapatite coating." in: Acta biomaterialia, Vol. 8, Issue 4, pp. 1627-38, (2012) (PubMed).
: "Human phosphoinositide 3-kinase C2beta, the role of calcium and the C2 domain in enzyme activity." in: The Journal of biological chemistry, Vol. 273, Issue 49, pp. 33082-90, (1999) (PubMed).
Synonyme und alternative Namen zu COL4a3
collagen type IV alpha 3 chain (COL4A3), collagen, type IV, alpha 3 (col4a3), collagen, type IV, alpha 3 (Col4a3), collagen type IV alpha 3 chain (Col4a3), alpha3(IV), zTumstatin, [a]3(IV)Bezeichner auf Proteinebene für COL4a3
- type IV collagen alpha 3 chain
- collagen alpha-3(IV) chain
- collagen type IV alpha3 chain
- procollagen, type IV, alpha 3
- tumstatin
- collagen, type IV, alpha 3 (Goodpasture antigen)
- collagen IV, alpha-3 polypeptide
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