Complement Factor B Produkte
(Complement Factor B (CFB))
Kategorien
This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2. [provided by RefSeq, Jul 2008].
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Ausgewählte Complement Factor B Kategorien
Complement Factor B Antikörper
High quality antibodies with extensive validation data.
Complement Factor B ELISA Kits
Reliable ELISA kits for a wide range of species.
Complement Factor B Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Complement Factor B Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, IF
Validierungen
- (7)
Kat. Nr.
ABIN3015550
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (5)
Kat. Nr.
ABIN7438322
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Rat
Applikation
WB, IHC, IP, ICC
Validierungen
- (5)
Kat. Nr.
ABIN7438376
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Complement Factor B ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (6)
Kat. Nr.
ABIN6720575
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (5)
- (4)
Kat. Nr.
ABIN6730898
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (5)
Kat. Nr.
ABIN6720576
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Complement Factor B Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Baculovirus infected Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN5854833
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN7092743
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Human Cells
Validierungen
Kat. Nr.
ABIN1096421
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Complement Factor B Produkten
: "Protein Expression Profile in Rat Silicosis Model Reveals Upregulation of PTPN2 and Its Inhibitory Effect on Epithelial-Mesenchymal Transition by Dephosphorylation of STAT3." in: International journal of molecular sciences, Vol. 21, Issue 4, (2020) (PubMed).: "Identification of susceptibility locus shared by IgA nephropathy and inflammatory bowel disease in a Chinese Han population." in: Journal of human genetics, Vol. 65, Issue 3, pp. 241-249, (2020) (PubMed).
: "Inhibition of Atypical Protein Kinase C Reduces Inflammation-Induced Retinal Vascular Permeability." in: The American journal of pathology, Vol. 188, Issue 10, pp. 2392-2405, (2018) (PubMed).
: "Viral mimic polyinosine-polycytidylic acid potentiates liver injury in trichloroethylene-sensitized mice - Viral-chemical interaction as a novel mechanism." in: Ecotoxicology and environmental safety, Vol. 155, pp. 101-108, (2018) (PubMed).
: "Adipose tissue complement factor B promotes adipocyte maturation." in: Biochemical and biophysical research communications, Vol. 495, Issue 1, pp. 740-748, (2017) (PubMed).
: "Acute and prolonged complement activation in the central nervous system during herpes simplex encephalitis." in: Journal of neuroimmunology, Vol. 295-296, pp. 130-8, (2016) (PubMed).
: "Depression of Complement Regulatory Factors in Rat and Human Renal Grafts Is Associated with the Progress of Acute T-Cell Mediated Rejection." in: PLoS ONE, Vol. 11, Issue 2, pp. e0148881, (2016) (PubMed).
: "Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B. ..." in: Hepatology (Baltimore, Md.), Vol. 62, Issue 1, pp. 118-28, (2015) (PubMed).
: "Atypical hemolytic uremic syndrome: Korean pediatric series." in: Pediatrics international : official journal of the Japan Pediatric Society, Vol. 57, Issue 3, pp. 431-8, (2015) (PubMed).
: "Identification and confirmation of differentially expressed fucosylated glycoproteins in the serum of ovarian cancer patients using a lectin array and LC-MS/MS." in: Journal of proteome research, Vol. 11, Issue 9, pp. 4541-52, (2012) (PubMed).
Synonyme und alternative Namen zu Complement Factor B
complement factor B (CFB), complement factor B (cfb), complement factor B (bf), complement factor B S homeolog (cfb.S), complement factor B L homeolog (cfb.L), complement factor B (bf/c2), complement factor B (LOC100555981), complement factor B (Cfb), AHUS4, AI195813, AI255840, B, BF, bf, Bf, Bf-1, bf/c2, Bf B, bfb-A, BFD, Brre-Bf, C2, CFAB, CFB, Da1-24, FB, Fb, FBI12, GBG, H2-Bf, LOC397725, PBF2, Sp152, zgc:114032Bezeichner auf Proteinebene für Complement Factor B
- B-factor, properdin
- C3 proaccelerator
- C3 proactivator
- C3/C5 convertase
- glycine-rich beta glycoprotein
- glycine-rich beta-glycoprotein
- properdin factor B
- complement component factor B
- complement factor B
- complement component 2
- EC-VMFB
- complement factor Bf-1
- Factor B
- alternative-complement pathway C3/C5 convertase
- complement component 2 (within H-2S)
- histocompatibility 2, complement component factor B
- properdin
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