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COPS8 Produkte

(COP9 Signalosome Subunit 8 (COPS8))

Kategorien

The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].

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Ausgewählte COPS8 Kategorien

COPS8 Antikörper

High quality antibodies with extensive validation data.

COPS8 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene COPS8 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (4)
Kat. Nr. ABIN524327
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (4)
Kat. Nr. ABIN6138889
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (3)
Kat. Nr. ABIN524324
Menge 50 μL
Datenblatt Datenblatt

Empfohlene COPS8 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6213819
Menge 96 tests
Datenblatt Datenblatt

Empfohlene COPS8 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN667600
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN2752761
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN2128659
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren COPS8 Produkten

Pick, Golan, Zimbler, Guo, Sharaby, Tsuge, Hofmann, Wei: "The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain." in: PLoS ONE, Vol. 7, Issue 8, pp. e43980, (2012) (PubMed).

Wei, Deng: "The COP9 signalosome." in: Annual review of cell and developmental biology, Vol. 19, pp. 261-86, (2003) (PubMed).

Uhle, Medalia, Waldron, Dumdey, Henklein, Bech-Otschir, Huang, Berse, Sperling, Schade, Dubiel: "Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome." in: The EMBO journal, Vol. 22, Issue 6, pp. 1302-12, (2003) (PubMed).

Groisman, Polanowska, Kuraoka, Sawada, Saijo, Drapkin, Kisselev, Tanaka, Nakatani: "The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage." in: Cell, Vol. 113, Issue 3, pp. 357-67, (2003) (PubMed).

Bech-Otschir, Seeger, Dubiel: "The COP9 signalosome: at the interface between signal transduction and ubiquitin-dependent proteolysis." in: Journal of cell science, Vol. 115, Issue Pt 3, pp. 467-73, (2002) (PubMed).

Synonyme und alternative Namen zu COPS8

COP9 signalosome subunit 8 (COPS8), COP9 signalosome subunit 8 (Cops8), COP9 signalosome subunit 8 (cops8), COP9 signalosome subunit 8 S homeolog (cops8.S), COP9 signalosome complex subunit 8 (CSN8), COP9 signalosome complex subunit 8 (csn8), COP9 signalosome subunit 8 L homeolog (cops8.L), COP9 signalosome, subunit CSN8 (COP9), COP9 signalosome subunit 8 (CSN8), 9430009J09Rik, AA408242, CG13383, CG33297, CG42522, CH8, CONSTITUTIVE PHOTOMORPHOGENIC 9, COP9, COP9 SIGNALOSOME SUBUNIT 8, cops8, CSN8, csn8, Csn8, Dch8, DDBDRAFT_0167123, DDBDRAFT_0233107, DDB_0167123, DDB_0233107, DL3095C, Dmel\\CG42522, Dmel_CG13383, EMB143, EMBRYO DEFECTIVE 143, FCAALL.131, FUS7, FUSCA 7, FUSCA PROTEIN FUS7, l(2)SH2 1829, l(2)SH1829, MGC76051, MGC80215, MGC86182, SGN8, Sgn8, zgc:56319, zgc:86840

Bezeichner auf Proteinebene für COPS8

  • COP9 constitutive photomorphogenic homolog subunit 8
  • COP9 homolog
  • COP9 signalosome complex subunit 8
  • JAB1-containing signalosome subunit 8
  • hCOP9
  • signalosome subunit 8
  • COP9 (constitutive photomorphogenic) homolog, subunit 8
  • SGN8
  • COP9 signalosome subunit 8
  • MGC80215 protein
  • COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)
  • CG42522-PB
  • CSN8-PB
  • Cop9 signalosome subunit 8
  • drosophila COP9 signalosome homolog 8
  • lethal (2) SH1829
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