Cortactin Produkte
(Cortactin (CTTN))
Kategorien
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010].
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Ausgewählte Cortactin Kategorien
Cortactin Antikörper
High quality antibodies with extensive validation data.
Cortactin ELISA Kits
Reliable ELISA kits for a wide range of species.
Cortactin Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Cortactin Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IHC (p), ICC
Validierungen
- (5)
- (1)
Kat. Nr.
ABIN2854674
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (6)
Kat. Nr.
ABIN6139243
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF, IP
Validierungen
- (7)
Kat. Nr.
ABIN7266511
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Cortactin ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1380549
Menge
2 x 96 tests
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1380550
Menge
2 x 96 tests
Datenblatt
Datenblatt
Empfohlene Cortactin Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1350743
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1350741
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (5)
- (1)
Kat. Nr.
ABIN2712518
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Cortactin Produkten
: "Clinical Characteristics of Patients With Double-Seronegative Myasthenia Gravis and Antibodies to Cortactin." in: JAMA neurology, Vol. 73, Issue 9, pp. 1099-104, (2016) (PubMed).: "PDCD10 (CCM3) regulates brain endothelial barrier integrity in cerebral cavernous malformation type 3: role of CCM3-ERK1/2-cortactin cross-talk." in: Acta neuropathologica, Vol. 130, Issue 5, pp. 731-50, (2015) (PubMed).
: "Identification of a novel myositis-associated antibody directed against cortactin." in: Autoimmunity reviews, Vol. 13, Issue 10, pp. 1008-12, (2014) (PubMed).
: "Cortactin autoantibodies in myasthenia gravis." in: Autoimmunity reviews, Vol. 13, Issue 10, pp. 1003-7, (2014) (PubMed).
: "Butyrophilin 3A1 plays an essential role in prenyl pyrophosphate stimulation of human V?2V?2 T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 3, pp. 1029-42, (2013) (PubMed).
: "Inhibitory member of the apoptosis-stimulating proteins of the p53 family (iASPP) interacts with protein phosphatase 1 via a noncanonical binding motif." in: The Journal of biological chemistry, Vol. 286, Issue 50, pp. 43039-44, (2011) (PubMed).
: "Cortactin promotes migration and platelet-derived growth factor-induced actin reorganization by signaling to Rho-GTPases." in: Molecular biology of the cell, Vol. 20, Issue 14, pp. 3209-23, (2009) (PubMed).
: "Involvement of dynamin-2 in formation of discoid vesicles in urinary bladder umbrella cells." in: Cell and tissue research, Vol. 337, Issue 1, pp. 91-102, (2009) (PubMed).
: "[Expression and clinical significance of EMS1 gene in gastric carcinoma]." in: Ai zheng = Aizheng = Chinese journal of cancer, Vol. 27, Issue 3, pp. 323-6, (2008) (PubMed).
: "Association of cortactin, fascin-1 and epidermal growth factor receptor (EGFR) expression in ovarian carcinomas: correlation with clinicopathological parameters." in: Disease markers, Vol. 25, Issue 1, pp. 17-26, (2008) (PubMed).
Synonyme und alternative Namen zu Cortactin
cortactin (CTTN), cortactin (Cttn), CG3637 gene product from transcript CG3637-RD (Cortactin), cortactin S homeolog (cttn.S), cortactin L homeolog (cttn.L), cortactin (cttn), src substrate cortactin (CpipJ_CPIJ006351), Src substrate cortactin (Bm1_57220), cortactin (LOC100533277), 1110020L01Rik, CG3637, cortactin, cttn, Cttn, CTTN, CTTN1, Cttnb, Dmel\CG3637, EMS1, Ems1, ems1, P85.25Bezeichner auf Proteinebene für Cortactin
- 1110020L01Rik
- amplaxin
- ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate)
- oncogene EMS1
- src substrate cortactin
- mammary tumor and squamous cell carcinoma associated (p80/85 src substrate)
- cortactin isoform B
- CG3637-PA
- CG3637-PB
- CG3637-PC
- CG3637-PD
- Cortactin-PA
- Cortactin-PB
- Cortactin-PC
- Cortactin-PD
- DCortactin
- cortactin
- p80
- p80/85
- src substrate protein p85
- Src substrate cortactin
- src substrate cortactin-like
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