Crk Produkte
(V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))
Kategorien
This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq, Jul 2008].
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Ausgewählte Crk Kategorien
Crk Antikörper
High quality antibodies with extensive validation data.
Crk ELISA Kits
Reliable ELISA kits for a wide range of species.
Crk Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Crk Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, ICC, FACS
Validierungen
- (2)
- (7)
Kat. Nr.
ABIN969062
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, PLA
Validierungen
- (4)
Kat. Nr.
ABIN514602
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Monkey, Mouse, Rat
Applikation
WB, ELISA, IF, ICC
Validierungen
- (4)
Kat. Nr.
ABIN6256674
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Crk ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6971097
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1380115
Menge
2 x 96 tests
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN5691928
Menge
2 x 96 tests
Datenblatt
Datenblatt
Empfohlene Crk Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7125676
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1350363
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1350365
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Crk Produkten
: "Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 5, pp. 1335-49, (2013) (PubMed).: "Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions." in: Proteomics, Vol. 13, Issue 14, pp. 2125-34, (2013) (PubMed).
: "Adaptor protein Crk induces Src-dependent activation of p38 MAPK in regulation of synovial sarcoma cell proliferation." in: Molecular cancer research : MCR, Vol. 7, Issue 9, pp. 1582-92, (2009) (PubMed).
: "[Biological roles of signaling adaptor protein CRK]." in: Seikagaku. The Journal of Japanese Biochemical Society, Vol. 81, Issue 5, pp. 361-76, (2009) (PubMed).
: "Avian and 1918 Spanish influenza a virus NS1 proteins bind to Crk/CrkL Src homology 3 domains to activate host cell signaling." in: The Journal of biological chemistry, Vol. 283, Issue 9, pp. 5719-27, (2008) (PubMed).
: "Signaling adaptor protein Crk is indispensable for malignant feature of glioblastoma cell line KMG4." in: Biochemical and biophysical research communications, Vol. 362, Issue 4, pp. 976-81, (2007) (PubMed).
: "The carboxyl-terminal SH3 domain of the mammalian adaptor CrkII promotes internalization of Listeria monocytogenes through activation of host phosphoinositide 3-kinase." in: Cellular microbiology, Vol. 9, Issue 10, pp. 2497-516, (2007) (PubMed).
: "RET/papillary thyroid carcinoma oncogenic signaling through the Rap1 small GTPase." in: Cancer research, Vol. 67, Issue 1, pp. 381-90, (2007) (PubMed).
: "Nck and Crk mediate distinct VEGF-induced signaling pathways that serve overlapping functions in focal adhesion turnover and integrin activation." in: Experimental cell research, Vol. 295, Issue 1, pp. 258-68, (2004) (PubMed).
: "Cortactin and Crk cooperate to trigger actin polymerization during Shigella invasion of epithelial cells." in: The Journal of cell biology, Vol. 166, Issue 2, pp. 225-35, (2004) (PubMed).
Synonyme und alternative Namen zu Crk
Crk oncogene (Crk), v-crk avian sarcoma virus CT10 oncogene homolog (crk), CRK proto-oncogene, adaptor protein (CRK), CRK proto-oncogene, adaptor protein (Crk), v-crk avian sarcoma virus CT10 oncogene homolog L homeolog (crk.L), v-crk sarcoma virus CT10 oncogene homolog (CRK), v-crk avian sarcoma virus CT10 oncogene homolog (Crk), c-Crk, CG1587, CRK, crk, Crk-I, Crk-II, Crk-III, crk2, Crk3, CRKII, crkII, CrkIII, Crko, D-CRK, D-Crk, DCrk, Dcrk, dCRK, dCrk, Dmel\\CG1587, fb34h10, fc05a01, fi19g05, p38, P38C-CRK, v-crk, wu:fb34h10, wu:fc05a01, wu:fc54a04, wu:fi19g05, zgc:100936Bezeichner auf Proteinebene für Crk
- CG1587-PA
- CG1587-PB
- CG1587-PC
- CG1587-PD
- CG1587-PE
- CG1587-PF
- Crk-PA
- Crk-PB
- Crk-PC
- Crk-PD
- Crk-PE
- Crk-PF
- adapter molecule crk
- v-crk sarcoma virus CT10 oncogene homolog (avian)
- proto-oncogene c-Crk
- avian sarcoma virus CT10 (v-crk) oncogene homolog
- p38
- proto-oncogene C-crk
- v-crk sarcoma virus CT10 oncogene homolog
- SH2/SH3 adaptor Crk2
- SH2/SH3 adaptor crk
- CT-10 related kinase 3
- proto-oncogene c-crk
- v-crk sarcoma virus CT10 oncogene-like protein
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