CrkL Produkte
(V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
Kategorien
This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.[provided by RefSeq, Jan 2009].
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Ausgewählte CrkL Kategorien
CrkL Antikörper
High quality antibodies with extensive validation data.
CrkL ELISA Kits
Reliable ELISA kits for a wide range of species.
CrkL Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CrkL Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF, PLA
Validierungen
- (1)
- (7)
Kat. Nr.
ABIN514605
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, PLA, RNAi
Validierungen
- (2)
- (8)
Kat. Nr.
ABIN514606
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, FACS
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN969064
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene CrkL ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6960414
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6960415
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1380116
Menge
2 x 96 tests
Datenblatt
Datenblatt
Empfohlene CrkL Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN667314
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1350367
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7408720
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CrkL Produkten
: "Increased Soluble CrkL in Serum of Breast Cancer Patients Is Associated with Advanced Disease." in: Cancers, Vol. 11, Issue 7, (2019) (PubMed).: "CRKL promotes lung cancer cell invasion through ERK-MMP9 pathway." in: Molecular carcinogenesis, Vol. 54 Suppl 1, pp. E35-44, (2015) (PubMed).
: "CRKL protein overexpression enhances cell proliferation and invasion in pancreatic cancer." in: Tumour biology, Vol. 36, Issue 2, pp. 1015-22, (2015) (PubMed).
: "Clinical significance and biological roles of CRKL in human bladder carcinoma." in: Tumour biology, Vol. 35, Issue 5, pp. 4101-6, (2014) (PubMed).
: "Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 5, pp. 1335-49, (2013) (PubMed).
: "Escherichia coli virulence protein NleH1 interaction with the v-Crk sarcoma virus CT10 oncogene-like protein (CRKL) governs NleH1 inhibition of the ribosomal protein S3 (RPS3)/nuclear factor κB ..." in: The Journal of biological chemistry, Vol. 288, Issue 48, pp. 34567-74, (2013) (PubMed).
: "Genomic and functional analysis identifies CRKL as an oncogene amplified in lung cancer." in: Oncogene, Vol. 29, Issue 10, pp. 1421-30, (2010) (PubMed).
: "Structural and functional basis of a role for CRKL in a fibroblast growth factor 8-induced feed-forward loop." in: Molecular and cellular biology, Vol. 29, Issue 11, pp. 3076-87, (2009) (PubMed).
: "PI3K links NKG2D signaling to a CrkL pathway involved in natural killer cell adhesion, polarity, and granule secretion." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 11, pp. 6933-42, (2009) (PubMed).
: "Active (p)CrkL is overexpressed in human malignancies: potential role as a surrogate parameter for therapeutic tyrosine kinase inhibition." in: Oncology reports, Vol. 15, Issue 2, pp. 353-9, (2006) (PubMed).
Synonyme und alternative Namen zu CrkL
CRK like proto-oncogene, adaptor protein (CRKL), v-crk avian sarcoma virus CT10 oncogene homolog-like (crkl), v-crk avian sarcoma virus CT10 oncogene homolog-like (Crkl), 1110025F07Rik, AA589403, AI325100, CRKL, Crkol, wu:fa55g05, wu:fj60e01, zgc:63469Bezeichner auf Proteinebene für CrkL
- v-crk sarcoma virus CT10 oncogene homolog (avian)-like
- crk-like protein
- v-crk sarcoma virus CT10 oncogene homolog-like
- v-crk avian sarcoma virus CT10 oncogene homolog-like
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