CTCF Produkte
(CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
Kategorien
This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].
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Ausgewählte CTCF Kategorien
CTCF Antikörper
High quality antibodies with extensive validation data.
CTCF ELISA Kits
Reliable ELISA kits for a wide range of species.
CTCF Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CTCF Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF, ChIP, IP
Validierungen
- (6)
Kat. Nr.
ABIN3021507
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ChIP-seq, CUT&RUN
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN6731034
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Monkey, Mouse, Rat
Applikation
IHC, IF
Validierungen
- (5)
Kat. Nr.
ABIN7255588
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene CTCF ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965536
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Chicken
Analytical Method
Validierungen
Kat. Nr.
ABIN1162630
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6213282
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene CTCF Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1350630
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (3)
- (1)
Kat. Nr.
ABIN1350629
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7122187
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CTCF Produkten
: "DNA methylation profiling in human Huntington's disease brain." in: Human molecular genetics, Vol. 25, Issue 10, pp. 2013-2030, (2016) (PubMed).: "The Human GATA1 Gene Retains a 5' Insulator That Maintains Chromosomal Architecture and GATA1 Expression Levels in Splenic Erythroblasts." in: Molecular and cellular biology, Vol. 35, Issue 10, pp. 1825-37, (2015) (PubMed).
: "Domain-Specific and Stage-Intrinsic Changes in Tcrb Conformation during Thymocyte Development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 3, pp. 1262-72, (2015) (PubMed).
: "CTCF binding to the first intron of the major immediate early (MIE) gene of human cytomegalovirus (HCMV) negatively regulates MIE gene expression and HCMV replication." in: Journal of virology, Vol. 88, Issue 13, pp. 7389-401, (2014) (PubMed).
: "Epigenetic control of SPI1 gene by CTCF and ISWI ATPase SMARCA5." in: PLoS ONE, Vol. 9, Issue 2, pp. e87448, (2014) (PubMed).
: "Friedreich ataxia patient tissues exhibit increased 5-hydroxymethylcytosine modification and decreased CTCF binding at the FXN locus." in: PLoS ONE, Vol. 8, Issue 9, pp. e74956, (2013) (PubMed).
: "Identification of CTCF as a master regulator of the clustered protocadherin genes." in: Nucleic acids research, Vol. 40, Issue 8, pp. 3378-91, (2012) (PubMed).
: "CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing." in: Nature, Vol. 479, Issue 7371, pp. 74-9, (2011) (PubMed).
: "DNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas." in: The Journal of experimental medicine, Vol. 207, Issue 9, pp. 1939-50, (2010) (PubMed).
: "Loss of imprinting of IGF2 and H19, loss of heterozygosity of IGF2R and CTCF, and Helicobacter pylori infection in laryngeal squamous cell carcinoma." in: Journal of molecular medicine (Berlin, Germany), Vol. 86, Issue 9, pp. 1057-66, (2008) (PubMed).
Synonyme und alternative Namen zu CTCF
CCCTC-binding factor (CTCF), CCCTC-binding factor (zinc finger protein) (ctcf), CCCTC-binding factor (ctcf), CCCTC-binding factor (Ctcf), AW108038, CTCF, im:7152666, xctcfBezeichner auf Proteinebene für CTCF
- transcriptional repressor CTCF
- CCCTC-binding factor (zinc finger protein)
- transcriptional repressor CTCF-like
- 11-zinc finger protein
- CTCFL paralog
- 11 zinc finger transcriptional repressor
Haben Sie etwas anderes gesucht?
- CTC1
- CTBS
- CTBP2
- CTBP1-AS1
- CTBP1
- CTAGE9
- CTAGE8
- CTAGE7P
- CTAGE6
- CTAGE4
- CTAGE3P
- CTAGE15
- CTAGE1
- CTAG2
- CTAG1B
- CTAG1A
- CT62
- CT47B1
- CT47A7
- CT47A5
- CTCFL
- CTD (Carboxy-Terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase Like 2
- CTD Nuclear Envelope Phosphatase 1 Regulatory Subunit 1
- CTDNEP1A
- CTDNEP1B
- CTDP1
- CTDSP1
- CTDSP2
- CTDSPL
- CTF18
- CTGF
- CTGLF11P
- CTH
- CTHRC1
- CTIF/KIAA0427
- CTK3
- CTLA-4 (Ipilimumab Biosimilar)
- CTLA-4 (Tremelimumab Biosimilar)
- CTLA2A
- Ctla2b
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