CTNNA1 Produkte
(Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1))
Kategorien
Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.
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Ausgewählte CTNNA1 Kategorien
CTNNA1 Antikörper
High quality antibodies with extensive validation data.
CTNNA1 ELISA Kits
Reliable ELISA kits for a wide range of species.
CTNNA1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CTNNA1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC, ELISA, IF, ICC
Validierungen
- (7)
Kat. Nr.
ABIN6260492
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP
Validierungen
- (8)
Kat. Nr.
ABIN6139202
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC
Validierungen
- (5)
Kat. Nr.
ABIN7261582
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene CTNNA1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6954435
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1380986
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Pig
Analytical Method
Quantitative
Validierungen
Kat. Nr.
ABIN778448
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene CTNNA1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1350658
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7412980
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN2713216
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CTNNA1 Produkten
: "TALENs-directed knockout of the full-length transcription factor Nrf1α that represses malignant behaviour of human hepatocellular carcinoma (HepG2) cells." in: Scientific reports, Vol. 6, pp. 23775, (2017) (PubMed).: "DLC1 interaction with ?-catenin stabilizes adherens junctions and enhances DLC1 antioncogenic activity." in: Molecular and cellular biology, Vol. 32, Issue 11, pp. 2145-59, (2012) (PubMed).
: "Loss of alpha-catenin decreases the strength of single E-cadherin bonds between human cancer cells." in: The Journal of biological chemistry, Vol. 284, Issue 27, pp. 18252-9, (2009) (PubMed).
: "Deconstructing the cadherin-catenin-actin complex." in: Cell, Vol. 123, Issue 5, pp. 889-901, (2005) (PubMed).
: "Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly." in: Cell, Vol. 123, Issue 5, pp. 903-15, (2005) (PubMed).
: "Regulation of beta-catenin signaling and maintenance of chondrocyte differentiation by ubiquitin-independent proteasomal degradation of alpha-catenin." in: The Journal of biological chemistry, Vol. 280, Issue 13, pp. 12758-65, (2005) (PubMed).
: "Gastric cancer: new genetic developments." in: Journal of surgical oncology, Vol. 90, Issue 3, pp. 114-33; discussion 133, (2005) (PubMed).
: "Prognostic and clinicopathological features of E-cadherin, alpha-catenin, beta-catenin, gamma-catenin and cyclin D1 expression in human esophageal squamous cell carcinoma." in: World journal of gastroenterology, Vol. 10, Issue 22, pp. 3235-9, (2005) (PubMed).
: "Characterization of cadherin-24, a novel alternatively spliced type II cadherin." in: The Journal of biological chemistry, Vol. 278, Issue 30, pp. 27513-9, (2003) (PubMed).
: "Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 5, pp. 2381-6, (2001) (PubMed).
Synonyme und alternative Namen zu CTNNA1
catenin alpha 1 (CTNNA1), catenin (cadherin associated protein), alpha 1 (Ctnna1), catenin alpha 1 (Ctnna1), alpha Catenin (alpha-Cat), alpha Catenin (Dgri\alpha-Cat), catenin alpha-1 (Tsp_10127), catenin (cadherin-associated protein), alpha 1 (ctnna1), catenin alpha 1 S homeolog (ctnna1.S), 2010010M04Rik, a-Cat, a-cat, AA517462, AI988031, alpha-CAT, alpha-cat, Alpha-Cat, alpha-catenin, alpha-ctn, alphaCAT, alphaCat, alphacat, CAP102, cap102, Catna1, catna1, CG17947, CT39986, ctnna, ctnna1, Dalpha-Cat, Dalpha-cat, DalphaC, Dalphacat, DgriGH19548, dgri_GLEANR_3829, Dmcatp, Dmel\\CG17947, GH19548Bezeichner auf Proteinebene für CTNNA1
- alpha E-catenin
- alpha-E-catenin
- alpha-catenin
- alphaE-catenin
- cadherin-associated protein,102kDa
- catenin alpha-1
- renal carcinoma antigen NY-REN-13
- a-catenin
- 102 kDa cadherin-associated protein
- CAP102
- alpha E catenin
- alpha(E)-catenin
- cadherin associated protein
- catenin alpha 1
- catenin (cadherin associated protein), alpha 1
- catenin, alpha 1
- CG17947-PA
- D-alpha-catenin
- Dalpha-Catenin
- Dalpha-cadherin
- DalphaCatenin
- alpha catenin
- alpha-Cat-PA
- alpha-Catenin
- alphaCatenin
- catenin alpha 1 subunit
- DgriGH19548-PA
- Dgrialpha-Cat-PA
- GH19548-PA
- catenin (cadherin-associated protein), alpha 1, 102kDa
- catenin alpha-1-like
- [a]E-catenin
- catenin alpha 1 S homeolog
- LOW QUALITY PROTEIN: catenin alpha-1
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